Holmer or Holmér is a surname. Notable people with the surname include:

• Gösta Holmér (1891–1983), Swedish decathlete
• Grethe Holmer (1924–2004), Danish actress
• Hans Holmér (1930–2002), Chief of the Swedish National Security Service, Stockholm county administrative chief of police
• M.R.N. Holmer (1875–1957), English university professor and writer who worked in India
• Richard Holmer (born 1945), professor of anthropology at Idaho State University
• Walt Holmer (1902–1976), American football quarterback and running back in the National Football League