| homoaconitate hydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Homoaconitate hydratase homodimer, Methanocaldococcus jannaschii | |||||||||
| Identifiers | |||||||||
| EC no. | 4.2.1.36 | ||||||||
| CAS no. | 9030-68-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme homoaconitate hydratase (EC 4.2.1.36) catalyzes the chemical reaction
- (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate (Z)-but-1-ene-1,2,4-tricarboxylate + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]. Other names in common use include homoaconitase, cis-homoaconitase, HACN, Lys4, LysF, and 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase (incorrect). This enzyme participates in lysine biosynthesis.
