House of Horror or House of Horrors may refer to:

In film and television

• House of Horror, a 1929 horror comedy film
• House of Horrors, a 1946 Universal Pictures horror film
• Hammer House of Horror, a television series produced by Hammer Film Productions
• New Line Cinema's House of Horror, a licensing division of New Line Cinema

Other uses

• Universal's House of Horrors, an attraction at the Universal Studios Hollywood theme park
• 25 Cromwell Street, sometimes referred to as the "house of horrors", a house associated with serial killers Fred West and Rosemary West
• "House Of Horrors", a song by horrorcore group Insane Clown Posse
• Turpin case, referred to as the "house of horrors"
• "House of Horrors match", a professional wrestling match between Bray Wyatt and Randy Orton that took place at WWE Payback (2017)
• Haunted attraction (simulated)