IMPA2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CZH, 2CZI, 2CZK, 2DDK, 2FVZ
Identifiers
Aliases	IMPA2, inositol monophosphatase 2
External IDs	OMIM: 605922 MGI: 2149728 HomoloGene: 22799 GeneCards: IMPA2
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18p11.21 Start 11,981,025 bp[1] End 12,030,877 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas skin of abdomen gastrocnemius muscle kidney vulva human penis vastus lateralis muscle gastric mucosa gums kidney tubule n/a More reference expression data BioGPS n/a
Gene ontology Molecular function inositol monophosphate 1-phosphatase activity inositol monophosphate phosphatase activity hydrolase activity protein binding protein homodimerization activity metal ion binding inositol monophosphate 3-phosphatase activity inositol monophosphate 4-phosphatase activity Cellular component cytoplasm cytosol Biological process phosphate-containing compound metabolic process phosphatidylinositol phosphate biosynthetic process inositol phosphate metabolic process inositol metabolic process inositol biosynthetic process signal transduction inositol phosphate dephosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3613 114663 Ensembl ENSG00000141401 n/a UniProt O14732 Q91UZ5 RefSeq (mRNA) NM_014214 NM_053261 RefSeq (protein) NP_055029 NP_444491 Location (UCSC) Chr 18: 11.98 – 12.03 Mb n/a PubMed search [2] [3]
Wikidata
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Inositol monophosphatase 2 is a 32 kDa enzyme that in humans is encoded by the IMPA2 gene.^[4][5] IMPA2 dephosphorylates myo-inositol monophosphate to myo-inositol.

The function of IMPA2 appears to be similar to IMPA1 within tissues; however, the genes are expressed differently in various tissues with IMPA2 expressed at the highest level in certain tissues of the brain and the lumen of the kidney. IMPA2 exists as a homodimer within cells and cannot form heterodimers with IMPA1.^[6]