interleukin 15 receptor, alpha
Identifiers
SymbolIL15RA
NCBI gene3601
HGNC5978
OMIM601070
RefSeqNM_172200
UniProtQ13261
Other data
LocusChr. 10 p15-10p14
Search for
StructuresSwiss-model
DomainsInterPro
interleukin 2 receptor, beta
Identifiers
SymbolIL2RB
Alt. symbolsCD122
NCBI gene3560
HGNC6009
OMIM146710
RefSeqNM_000878
UniProtP14784
Other data
LocusChr. 22 q13
Search for
StructuresSwiss-model
DomainsInterPro
interleukin 2 receptor, gamma (severe combined immunodeficiency)
Identifiers
SymbolIL2RG
Alt. symbolsSCIDX1, IMD4
NCBI gene3561
HGNC6010
OMIM308380
RefSeqNM_000206
Other data
LocusChr. X q13

Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with the IL-2 receptor.[2]

References

  1. ^ PDB: 2B5I​Wang X, Rickert M, Garcia KC (November 2005). "Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors". Science. 310 (5751): 1159–63. Bibcode:2005Sci...310.1159W. doi:10.1126/science.1117893. PMID 16293754. S2CID 85394260.((cite journal)): CS1 maint: date and year (link)
  2. ^ Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA (1995). "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. Biol. Chem. 270 (50): 29862–9. doi:10.1074/jbc.270.50.29862. PMID 8530383.

External links


Cytokine receptors
Interleukin receptor modulators
Categories