Intermediate trophoblast is a distinct subtype of trophoblastic tissue that arises from the cytotrophoblast.[1]
It is sub-categorized by location:[1]
- Villous intermediate trophoblast:
- at anchoring villi of trophoblastic column
- Implantation site intermediate trophoblast:
- at implantation site (or basal plate), differentiated from villous intermediate trophoblast
- Chorionic-type intermediate trophoblast
- at chorionic laeve of fetal membrane, differentiated from villous intermediate trophoblast
Function
The function of the implantation site intermediate trophoblast is to anchor the placenta to the maternal tissue.
Pathology
Intermediate trophoblasts are thought to be the cell of origin for:[1]