Intermittent fasting (IF) is an umbrella term for various diets that cycle between a period of fasting and non-fasting. Intermittent fasting can be used along with calorie restriction for weight loss.[1]
Most popular intermittent fasting protocols can be grouped into 3 categories: alternate day fasting (ADF), whole-day fasting, and time-restricted feeding (TRF).
Alternate day fasting (ADF) involves a 24-hour fast followed by a 24-hour non-fasting period.[2] One can choose fasting 23 hours with one meal per day.[3]
Whole-day fasting specifies various ratios of fasting to non-fasting days, such as the 5:2 diet in which people consumed 400–500 calories (women) or 500–600 calories (men) during the days of fasting. During feed days, the diet was regular.[4]
Time-restricted feeding (TRF) involves a set daily fasting period and shortened eating window of 3–12 hours.[5] For example, one form of TRF calls for fasting for 16 hours each day and eating total daily calories during the remaining 8 hours, typically on the same schedule each day.[6]
In some contexts, fasting allows the consumption of a limited amount of low-calorie beverages such as coffee or tea. This modified fasting involves limiting caloric intake (e.g., 20% of normal) during fasted periods rather than none at all,[2] possibly retaining most of the benefits of intermittent fasting.
A 2014 review[7] described that intermittent fasting has not been studied in children, the elderly, or the underweight, and could be harmful in this population. It also suggested that people choosing to fast for periods of time greater than 24 hours should be monitored by a physician, as changes to the gastrointestinal system or circadian rhythm can occur.[7] The review concluded that fasting is unlikely to have much effect on conditions other than obesity, such as aging or other chronic condition, unless combined with moderate calorie restriction and a plant-based diet such as the Mediterranean diet.[7]
According to another 2014 review, intermittent fasting can lead to weight loss, though long-term calorie restriction can lead to slightly more weight loss compared to intermittent fasting.[8]