Irwin is an Irish, Scottish, and English surname stemming from the surname Eoforwine, a combination of the Old English words for boar and friend.^[1] Notable people with the surname include:

• Alexander Irwin (died 1752), British Army officer
• Alexander J. Irwin (1799–1843), United States territorial legislator
• Andy Offutt Irwin, American storyteller and singer/songwriter
• Arthur Irwin (1858–1921), Canadian-American shortstop and manager in Major League Baseball
• Ashton Irwin (born 1994), Australian drummer in the band 5 Seconds of Summer
• Bill Irwin (wrestler), professional wrestler
• Bill Irwin (born 1950), American actor and clown
• Charles Irwin (1824–1873), Irish recipient of the Victoria Cross
• Clint Irwin (born 1989), American soccer goalkeeper
• Denis Irwin (born 1965), Irish footballer
• Dennis Irwin (1951–2008), American jazz musician
• Elaine Irwin, American supermodel and spokeswoman for Almay Cosmetics
• Francis Xavier Irwin (1934–2019), American Roman Catholic bishop
• Frederick Irwin (1788–1860), acting Governor of Western Australia
• George Rankine Irwin (1907–1998), American scientist specializing in fracture mechanics
• Hale Irwin (born 1945), American golfer
• Heath Irwin (born 1973), American football player (nephew of Hale)
• Herbert Carmichael Irwin (1894–1930), Irish-born aviator and athlete
• Inez Haynes Irwin (1873–1970), American feminist author
• J. David Irwin, electrical engineering educator
• James Irwin (disambiguation), several people
• James Bruce Irwin (1921–2012), New Zealand botanist
• Sir James Murray Irwin (1858–1938), British Army doctor who served in Sudan, the Boer War and the Great War
• Jared Irwin (1750–1818), Governor of Georgia
• Jeff Irwin, American musician
• Jennifer Irwin (born 1975), Canadian actress
• John N. Irwin (1844–1905), American politician and Governor of Idaho Territory (1883) and Arizona Territory (1890–1892)
• John Rice Irwin (1930–2022), American cultural historian
• John N. Irwin, II (1913–2000), American diplomat
• Jonnie Irwin (1973–2024), English television presenter and property consultant
• Julia Irwin, Australian politician
• Julienne Irwin, American singer
• Kenny Irwin Jr. (1969–2000), American racing driver
• Les Irwin (1898–1985), Australian politician
• Lew Irwin, radio broadcaster and founder of The Credibility Gap
• Malcolm Robert Irwin (1897–1987), American immunogeneticist
• Matt Irwin (born 1987), Canadian ice hockey player
• May Irwin (1862–1938), actress, singer and major star of vaudeville
• Michael Irwin (disambiguation), several people
• Noel Irwin (1892–1972), British World War II general
• Pat Irwin, (born 1955) American composer and musician
• Pat Irwin, (1921–1999), Oklahoma judge
• Patrick H. Irwin (1837–1908), American civil engineer and surveyor
• Robert Irwin (disambiguation), several people
• Ron Irwin (1936–2020), Canadian politician
• Scott Irwin, professional wrestler and brother of Bill Irwin
• Steve Irwin (1962–2006), Australian conservationist and television personality
  • Bob Irwin (born 1939), Steve's father, Australian naturalist
  • Terri Irwin (born 1964), Steve's widow, American-born naturalist
  • Bindi Irwin (born 1998), Steve and Terri's daughter, Australian television personality
  • Robert Irwin (television personality) (born 2003), Steve and Terri's son, Australian television personality
• Steve Irwin, Australian rugby league footballer
• Stu Irwin (1903–1967), American actor
• Trenton Irwin (born 1995), American football player
• William Irwin (disambiguation), various people named William or Bill Irwin
• E. F. L. Wood, 1st Earl of Halifax, created Baron Irwin in 1926