Isabella of Spain or Isabel of Spain may refer to:

• Isabella I of Castile (1451–1504), queen
• Isabella II of Spain (1830–1904), queen
• Isabella of Austria (1501–1526)
• Infanta Isabella Clara Eugenia of Spain (1566–1633), archduchess of the Netherlands
• María Isabella of Spain (1789–1848)
• Isabella, Princess of Asturias (1851–1931)

• Isabella, Princess of Asturias (disambiguation)
• Isabella of Castile (disambiguation)

Topics referred to by the same term

This disambiguation page lists articles about people with the same name.
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