Janine is a feminine given name and may refer to:

People

• Janine Balding (1967–1988), Australian murder victim
• Janine Bazin (1923–2003), French film and television producer
• Janine Beermann (born 1983), German field hockey player
• Janine Berdin (born 2002), Filipina singer
• Janine Charrat (1924–2017), French dancer and choreographer
• Janine Duvitski (born 1952), English actress
• Janine Flock (born 1989), Austrian skeleton racer
• Janine P. Geske (born 1949), American jurist and law professor
• Janine Greiner (born 1981), Swiss curler
• Janine Gutierrez (born 1989), Filipina actress and television host
• Janine Haines (1945–2004), Australian politician
• Janine Harouni (fl. 2010's) UK based American comedian and actress
• Janine Irons, British music educator, artist manager and producer
• Janine Kohlmann (born 1990), German modern pentathlete
• Janine Leal (born 1976), Venezuelan television presenter and model.
• Janine Lindemulder (born 1968), American exotic dancer and adult film actress
• Janine Pommy Vega (1942–2010), American poet
• Janine Rozier (born 1938), French senator
• Janine Thompson (born 1967), Australian tennis player
• Janine Tugonon (born 1989), Filipino model, TV presenter and beauty pageant titleholder
• Janine Turner (born 1962), American actress
• Janine van Wyk (born 1987), South African women's footballer
• Janine Zacharia, American journalist

Fictional characters

• Janine Butcher, in EastEnders
• Janine Nebeski, in Bad Girls
• Janine (Pokémon), in the Pokémon universe
• Janine Melnitz, in the Ghostbusters films
• Janine Stifler, aka Stifler's Mom, in the American Pie film series
• Janine, a recurring character in sitcom Friends played by Elle Macpherson
• Janine, a fictional character from Witch and Wizard, a novel by James Patterson
• Janine, the previous name of Ofwarren, a fictional character from The Handmaid's Tale, a novel by Margaret Atwood