John Skelton may refer to:

• John Skelton (poet) (c.1460–1529), English poet.
• John Skelton, MP for Cumberland, 1390–1458
• John Skelton (died 1439), MP for Cumberland (UK Parliament constituency)
• John Skelton (American football) (born 1988), American football quarterback
• John Skelton (sculptor) (1923–1999), letterer and sculptor
• John Skelton (author) (1831–1897) Scottish lawyer, historian, biographer, literary correspondent and writer on social problems
• John Skelton (herbalist), British herbalist