Josef Coresh
Academic background
EducationBS, Mathematics, Princeton University
MHS, PhD, 1992, Johns Hopkins Bloomberg School of Public Health
MD, 1992, Johns Hopkins University
ThesisGenetic epidemiology of Apolipoprotein B (1992img)
Academic work
InstitutionsJohns Hopkins University

Josef Coresh is an American epidemiologist. He is the inaugural George W. Comstock Professor in the Department of Epidemiology at Johns Hopkins University. Coresh serves as the director of both the Cardiovascular Epidemiology Training Program and the George W. Comstock Center for Public Health Research and Prevention at the Johns Hopkins School of Medicine.

Early life and education

Coresh attended Princeton University for his bachelor's degree in mathematics before enrolling at Johns Hopkins University for his medical degree, master's degree, and PhD.[1]

Career

During his tenure at Johns Hopkins, Coresh studies risk factors for vascular disease across different organs including the heart, kidney and brain with the goal of improving health and research. He developed a population-based longitudinal proteomic study of health in the ARIC (Atherosclerosis Risk in Communities) Study population. He used data of nearly 5000 proteins over three decades to gain insights into novel risk factors and pathways for dementia, heart disease, cancer and aging.[2][3] Coresh also led the Cardiovascular Epidemiology Training Program at the Bloomberg School since 1997.[4] In this role, he was recognized with the AHA Lifestyle Council Mentorship Award as "a person who has provided exceptional individual and institutional mentoring and advocacy for cardiovascular epidemiology researchers."[5] His mentees included Elizabeth Selvin[6] and Morgan Grams.[7]

In 2007, his paper "Prevalence of chronic kidney disease in the United States" was ranked by Essential Science Indicators as one of the 20 most-cited "Hot Papers" over all fields and a "Highly Cited Paper in Clinical Medicine."[8] The following year, he was appointed both the Cardiovascular Epidemiology Training Program and the George W. Comstock Center for Public Health Research and Prevention at the Johns Hopkins School of Medicine.[9] Later, Coresh was appointed vice-chair of the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative workgroup (for the Clinical Practice Guideline "Chronic Kidney Disease: Evaluation, Classification and Stratification") which has also led to his increased involvement in the international effort to address the public health burden of chronic kidney disease.[8] In 2009, Coresh was the co-author of "Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout" which received the PNAS paper Cozzarelli Prize for outstanding scientific excellence and originality.[10] The following year, the National Kidney Foundation gave Coresh the Garabed Eknoyan Award for his contributions to the field. He was also the recipient of the American Heart Association's Epidemiology and Prevention Mentoring Award.[8]

As the leader of the Chronic Kidney Disease Prognosis Consortium, Coresh analyzed data from 1.7 million participants recruited into 35 cohorts in dozens of countries from 1975 to 2011 and followed for an average of 5 years. He used this data to suggest that new therapies for kidney disease by revising the definition of kidney disease progression used during clinical trials.[11] Due to his overall research, Coresh was the recipient of the 2015 National Kidney Foundation's David Hume Award, their highest honor given to individuals "who exemplifies the high ideals of scholarship and humanism in an outstanding manner."[12]

In fall 2020, Coresh co-authored a kidney study using international data from over nine million individuals "to develop and validate a risk-scoring calculation that adds blood and urine measures of kidney disease to the current standard method in the United States for assessing cardiovascular disease risk."[13] In October, he was the recipient of the Belding H. Scribner Lifetime Achievement Award from the American Society of Nephrology for his career-long contributions to the practice of nephrology.[14]

References

  1. ^ "Josef Coresh, M.D., Ph.D." hopkinsmedicine.org. Retrieved April 7, 2021.
  2. ^ Alonso, A.; Lopez, F. L.; Matsushita, K.; Loehr, L. R.; Agarwal, S. K.; Chen, L. Y.; Soliman, E. Z.; Astor, B. C.; Coresh, J. (June 28, 2011). "Chronic Kidney Disease is Associated with the Incidence of Atrial Fibrillation: the Atherosclerosis Risk in Communities (ARIC) Study". Circulation. 123 (25): 2946–2953. doi:10.1161/CIRCULATIONAHA.111.020982. PMC 3139978. PMID 21646496.
  3. ^ Coresh, Josef. "ARIC Neurocognitive Study (ARIC-NCS) 1 of 5". grantome.com. Retrieved April 10, 2021.
  4. ^ "Josef Coresh". professorships.jhu.edu. Retrieved April 10, 2021.
  5. ^ "Dr. Josef Coresh Receives National Mentoring Award". hopkinsmedicine.org. 2010. Retrieved April 10, 2021.
  6. ^ "Elizabeth Selvin a Winner in 2005 Postdoctoral Fellows' Poster Competition". jhsph.edu. 2005. Retrieved April 10, 2021.
  7. ^ Fischer, Renee (March 19, 2015). "COMSTOCK PROFESSOR JOSEF KORESH ADVANCES EPIDEMIOLOGICAL RESEARCH". giving.jhu.edu. Retrieved April 10, 2021.
  8. ^ a b c "Coresh Receives Multiple Honors". jhsph.edu. April 12, 2010. Retrieved April 9, 2021.
  9. ^ Coresh, Josef; Platz, Elizabeth A. (March 1, 2016). "The George W. Comstock Center for Public Health Research and Prevention: A Century of Collaboration, Innovation, and Translation". American Journal of Epidemiology. 183 (5): 362–366. doi:10.1093/aje/kwv261. PMC 4772436. PMID 26872712. Retrieved April 10, 2021.
  10. ^ "PNAS announces six 2009 Cozzarelli Prize recipients". eurekalert.org. Eurekalert. February 23, 2010. Retrieved April 9, 2021.
  11. ^ "New definition of kidney disease for clinical trials could lead to new treatments". eurekalert.org. Eurekalert. June 3, 2014. Retrieved April 9, 2021.
  12. ^ "Renowned Kidney Disease Expert to Receive National Kidney Foundation's Highest Honor". kidney.org. National Kidney Foundation. March 19, 2015. Retrieved April 9, 2021.
  13. ^ "Researchers improve the standard method for assessing cardiovascular disease risk". eurekalert.org. Eurekalert. October 14, 2020. Retrieved April 9, 2021.
  14. ^ "ASN to Bestow Belding H. Scribner Award on Josef Coresh". kidneynews.org. October 2020. Retrieved April 9, 2021.

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