KCND1
Identifiers
Aliases	KCND1, KV4.1, potassium voltage-gated channel subfamily D member 1
External IDs	OMIM: 300281 MGI: 96671 HomoloGene: 21035 GeneCards: KCND1
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.23 Start 48,961,378 bp[1] End 48,971,844 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X A1.1|X 3.53 cM Start 7,688,528 bp[2] End 7,704,519 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left uterine tube stromal cell of endometrium ascending aorta left coronary artery gallbladder smooth muscle tissue right coronary artery gastric mucosa prefrontal cortex cerebellar vermis Top expressed in facial motor nucleus anterior horn of spinal cord superior frontal gyrus trigeminal ganglion calvaria submandibular gland neural tube cerebellar cortex renal corpuscle yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function potassium channel activity metal ion binding voltage-gated ion channel activity ion channel activity A-type (transient outward) potassium channel activity voltage-gated potassium channel activity Cellular component integral component of membrane cell projection membrane voltage-gated potassium channel complex plasma membrane neuronal cell body dendrite cellular component Biological process regulation of ion transmembrane transport ion transport potassium ion transport transmembrane transport potassium ion transmembrane transport protein homooligomerization cardiac conduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3750 16506 Ensembl ENSG00000102057 ENSMUSG00000009731 UniProt Q9NSA2 Q03719 RefSeq (mRNA) NM_004979 NM_008423 RefSeq (protein) NP_004970 NP_032449 Location (UCSC) Chr X: 48.96 – 48.97 Mb Chr X: 7.69 – 7.7 Mb PubMed search [3] [4]
Wikidata
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Potassium voltage-gated channel, Shal-related subfamily, member 1 (KCND1), also known as K_v4.1, is a human gene.^[5]

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle.^[5]