ABRAXAS2
Identifiers
Aliases	ABRAXAS2, ABRO1, KIAA0157, FAM175B, family with sequence similarity 175 member B, abraxas 2, BRISC complex subunit
External IDs	OMIM: 611144 MGI: 1926116 HomoloGene: 12970 GeneCards: ABRAXAS2
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.13 Start 124,801,819 bp[1] End 124,836,667 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 132,460,954 bp[2] End 132,486,840 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte middle temporal gyrus Brodmann area 23 deltoid muscle gastrocnemius muscle Achilles tendon parietal pleura visceral pleura tibialis anterior muscle vastus lateralis muscle Top expressed in Paneth cell superior cervical ganglion otolith organ utricle hand ureter foot temporal muscle facial motor nucleus sternocleidomastoid muscle More reference expression data BioGPS n/a
Gene ontology Molecular function microtubule binding polyubiquitin modification-dependent protein binding protein binding Cellular component cytoplasm centrosome spindle pole BRISC complex spindle pole centrosome midbody microtubule cytoskeleton nucleus microtubule minus-end cytosol Biological process chromosome segregation cell division mitotic spindle assembly response to ischemia protein K63-linked deubiquitination cell cycle attachment of spindle microtubules to kinetochore protein deubiquitination mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23172 109359 Ensembl ENSG00000165660 ENSMUSG00000030965 UniProt Q15018 Q3TCJ1 RefSeq (mRNA) NM_032182 NM_198017 RefSeq (protein) NP_115558 NP_932134 Location (UCSC) Chr 10: 124.8 – 124.84 Mb Chr 7: 132.46 – 132.49 Mb PubMed search [3] [4]
Wikidata
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BRISC complex subunit Abro1 is a protein that in humans is encoded by the FAM175B gene.^[5][6]