KRT33B
Identifiers
Aliases	KRT33B, HA3II, Ha-3II, K33B, KRTHA3A, KRTHA3B, hHa3-II, keratin 33B
External IDs	OMIM: 602762 HomoloGene: 136754 GeneCards: KRT33B
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,363,498 bp[1] End 41,369,813 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex skin of abdomen Brodmann area 9 right lung vagina hippocampus proper minor salivary gland muscle tissue muscle of leg gastrocnemius muscle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding structural molecule activity Cellular component extracellular exosome intermediate filament extracellular space cytosol Biological process hair cycle human ageing keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3884 n/a Ensembl ENSG00000263012 ENSG00000131738 n/a UniProt Q14525 n/a RefSeq (mRNA) NM_002279 n/a RefSeq (protein) NP_002270 n/a Location (UCSC) Chr 17: 41.36 – 41.37 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.^[3][4][5]

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.^[5]