Karl Binz (1 July 1832 – 11 January 1913) was a German physician and pharmacologist born in Bernkastel. He is known for his investigations on the pharmacological properties and effects of quinine.[1]
In 1867 he discovered that quinine was highly toxic to micro-organisms in impure water,[2] and demonstrated that quinine hydrochlorate with neutral or slightly basic reaction was an effective poison for the protoplasms of decomposing plants and impeded many fermenting and putrid processes.[3] In addition to his research of quinine, he performed extensive pharmacological tests on arsenic, halogens and associated compounds, sleep-inducing substances, et al. The eponymous "Binz' test" is a qualitative test for the presence of quinine in urine.[4]
Selected writings
Ueber die Wirkung antiseptischer Stoffe auf Infusorien von Pflanzenjauche, (Centralblatt der med. Wissenschaften, V/20), 1867 – On the effect of antiseptic substances on infusoria of plant pests.
Experimentelle Beobachtungen über das Wesen der Chininwirkung, 1868 – Experimental observations on the nature of quinine.
Weitere Studien über Chinin. (Berliner Klinische Wochenschrift, November 1871), 1871 – Further studies about quinine.
Das Chinin nach den neueren pharmakologischen Arbeiten, 1876 – Quinine according to recent pharmacological work.
Ueber den Traum (1878).
La quinine prophylactique de la fièvre de la malaria (1890, by Binz and other scientists) – Quinine for treatment of the fever of malaria.[5]
Vorlesungen über Pharmakologie, 1891 – Lessons on pharmacology.
Binz was also the author of a number of works in the field of "history of medicine", such as:
Doktor Johann Weyer, ein rheinischer Arzt, der erste Bekämpfer des Hexenwahns, (1885, second edition 1896) – Doctor Johann Weyer, a Rhenish physician, first fighter of the witch craze.
Augustin Lercheimer (Professor H. Witekind in Heidelberg) und seine Schrift wider den Hexenwahn, 1888 – Augustin Lercheimer (Professor H. Witekind in Heidelberg) and his publications against the witch craze.
Die Einschleppung der Syphilis in Europa, 1893 – The introduction of syphilis in Europe.[7]
Aether gegen den Schmerz, 1896 – Ether against the pain.
^Lehrer, Steven (2006). Explorers of the Body: Dramatic Breakthroughs in Medicine from Ancient Times to Modern Science. iUniverse. p. 244. ISBN978-0-595-40731-6.
^The Living Age. Vol. 199. Littell, Son and Company. 1893. p. 192.