Kentucky Route 388
Route information
Maintained by KYTC
Length	12.937 mi[1] (20.820 km)
Major junctions
South end	US 25 Bus. / KY 52 / South Second Street in Richmond
North end	KY 627 at Boonesborough
Location
Country	United States
State	Kentucky
Counties	Madison
Highway system
Kentucky State Highway System Interstate US State Parkways
← KY 387 → KY 389

Kentucky Route 388 (KY 388) is a 12.937-mile (20.820 km) state highway in Madison County, Kentucky, that runs from U.S. Route 25 Business, Kentucky Route 52, and South Second Street in downtown Richmond to Kentucky Route 627 just to the west of Boonesborough. The route passes through Fort Boonesborough State Park, and also comes within 0.5 miles (0.80 km) of Clark County.

Major intersections

The entire route is in Madison County.

Location	mi[1]	km	Destinations	Notes
Richmond	0.000	0.000	US 25 Bus. / KY 52 (West Main Street) / South Second Street	Southern terminus; continues as South Second Street beyond US 25 Bus. / KY 52
​	1.967	3.166	KY 1986 (Union City Road) – Union City, Doylesville
Redhouse	6.259	10.073	KY 3377 west (Lost Fork Road)	Eastern terminus of KY 3377
Boonesborough	12.937	20.820	KY 627 (Boonesborough Road)	Northern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi