This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: "LAE-32" – news · newspapers · books · scholar · JSTOR (December 2016) (Learn how and when to remove this message) The topic of this article may not meet Wikipedia's general notability guideline. Please help to demonstrate the notability of the topic by citing reliable secondary sources that are independent of the topic and provide significant coverage of it beyond a mere trivial mention. If notability cannot be shown, the article is likely to be merged, redirected, or deleted.Find sources: "LAE-32" – news · newspapers · books · scholar · JSTOR (November 2021) (Learn how and when to remove this message) (Learn how and when to remove this message)
Clinical data
Other namesLAE; Lysergic acid ethylamide; d-Lysergic acid ethylamide; d-Ethyllysergamide,
Routes of
Pharmacokinetic data
  • (8β)-N-Ethyl-6-methyl-9,10-didehydroergoline-8-carboxamide
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass295.386 g·mol−1
3D model (JSmol)
  • CCNC(=O)[C@@H]2C=C1c3cccc4[nH]cc(C[C@H]1N(C)C2)c34
  • InChI=1S/C18H21N3O/c1-3-19-18(22)12-7-14-13-5-4-6-15-17(13)11(9-20-15)8-16(14)21(2)10-12/h4-7,9,12,16,20H,3,8,10H2,1-2H3,(H,19,22)/t12-,16-/m1/s1 checkY

D-Lysergic acid ethylamide (LAE-32) is a derivative of ergine.[1][2] It is reported to have some LSD-like effects but is weaker and shorter lasting, with an active dose reported to be between 0.5 and 1.5 milligrams.

It was studied by the CIA as part of Project MKULTRA. Documents published by the CIA under the Freedom of Information Act suggest it causes "a schizophrenia-like condition" but it allows people with schizophrenia to remain indifferent to their disorder.


  1. ^ "N-Ethyllysergamide". PubChem. U.S. National Library of Medicine. Retrieved 2022-11-16.
  2. ^ Baquiran M, Al Khalili Y (2022). "Lysergic Acid Diethylamide Toxicity". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 31985997. Retrieved 2022-11-18.