The Last Train may refer to:

Film and television

• The Last Train (2002 film), a Uruguayan and Argentinian comedy-drama film
• The Last Train (2006 film), a German drama
• The Last Train (TV series), a 1999 British, six-part, post-apocalyptic television drama series
• The Last Train, winner of the 2003 Thessaloniki International Film Festival

Other uses

• Last Train (bridge), a bidding convention in the card game contract bridge
• "Last Train" (Christine Anu and Paul Kelly song), 1993
• "Last Train" (Tiësto and Firebeatz song), 2014
• "The Last Train", a 1950 short story by Fredric Brown
• "The Last Train", a song by Mondo Generator from the 2012 album Hell Comes to Your Heart