Leona is a female given name derived from the Latin word leo for "lion".

People and fictional characters named Leona include:

People

• Leona (wrestler) (born 1980), Japanese professional wrestler
• Leona Aglukkaq, Canadian politician
• Leona Brown, American boxer
• Leona Cavalli, Brazilian actress
• Leona Dalrymple, American author
• Leona Dombrowsky, Canadian politician
• Leona Florentino, Philippine poet
• Leona Gom, Canadian novelist and poet
• Leona Graham, British DJ and voiceover artist
• Leona Helmsley, American hotel operator and real estate investor
• Leona Hutton, American silent film star
• Leona Lewis (born 1985), British singer-songwriter
• Leona Mitchell, American soprano
• Leona Naess (born 1974), British singer-songwriter
• Leona Popović (born 1997), Croatian alpine ski racer
• Leona Roberts (1879–1954), American stage and film actress
• Leona Vidal Roberts (born 1972), Falkland Islands politician
• Leona Vaughan (born 1995), Welsh actress
• Leona Vicario, Mexican, supporter of the Mexican War of Independence
• Leona Woods, American physicist

Fictional characters

• Leona Heidern, in The King of Fighters video game series
• Leona Ozaki, in Masamune Shirow's Dominion anime and manga series
• Leona, the Radiant Dawn, a playable champion character in the multiplayer online battle arena video game League of Legends
• Leona, from the TV series Between the Lions
• Leaky Leona, a character from the third season of the TV series Codename: Kids Next Door