Lidoflazine

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	C08EX01 (WHO)
Identifiers
IUPAC name 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,6-dimethylphenyl)acetamide
CAS Number	3416-26-0 Y
PubChem CID	3926
ChemSpider	3789 N
UNII	J4ZHN3HBTE
KEGG	D04733 Y
CompTox Dashboard (EPA)	DTXSID6045377
ECHA InfoCard	100.020.285
Chemical and physical data
Formula	C30H35F2N3O
Molar mass	491.627 g·mol−1
3D model (JSmol)	Interactive image
Melting point	159 to 161 °C (318 to 322 °F)
Solubility in water	Almost insoluble in water(<0.01%); Very soluble in chloroform(>50%); mg/mL (20 °C)
SMILES CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
InChI InChI=1S/C30H35F2N3O/c1-22-5-3-6-23(2)30(22)33-29(36)21-35-19-17-34(18-20-35)16-4-7-28(24-8-12-26(31)13-9-24)25-10-14-27(32)15-11-25/h3,5-6,8-15,28H,4,7,16-21H2,1-2H3,(H,33,36) N Key:ZBIAKUMOEKILTF-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action.^[1] Lidoflazine was discovered at Janssen Pharmaceutica in 1964.

Physical properties

Solubility at room temperature

Extracted from^[1]