Grand Prix motorcycle racing is the premier championship of motorcycle road racing, which has been divided into three classes since 1990; 125cc, 250cc and MotoGP. Former classes that are now discontinued include 350cc, 50cc and sidecars.^[1] The premier class is MotoGP, which was formerly known as the 500cc class.^[1] The Grand Prix Road-Racing World Championship was established in 1949 by the sport's governing body the Fédération Internationale de Motocyclisme (FIM), and is the oldest motorsport World Championship in existence.^[2] The motorcycles used in MotoGP are purpose-built for the sport, and are unavailable for purchase by the general public: they cannot be legally ridden on public roads.^[2]

Honda holds the record for the most Grand Prix victories on the premier class, having won 313 times. Yamaha is second with 245 wins, and MV Agusta is third with 139 wins.

By constructor

As of the 2023 Valencian Grand Prix

Grand Prix motorcycle racing winners

Rank	Country	Constructor	Wins	Seasons active	First win	Last win
1	JPN	Honda*	313	1966–1972, 1979–	1966 500cc West German Grand Prix	2023 MotoGP Grand Prix of the Americas
2	JPN	Yamaha*	245	1968–	1972 500cc Spanish Grand Prix	2022 MotoGP German Grand Prix
3	ITA	MV Agusta*	139	1950–1976	1952 500cc Nations Grand Prix	1976 500cc West German Grand Prix
4	JPN	Suzuki*	97	1971–2011, 2014–2022	1971 500cc Ulster Grand Prix	2022 MotoGP Valencian Grand Prix
5	ITA	Ducati*	87	1965, 1968, 1970–1973, 2003–	2003 MotoGP Catalan Grand Prix	2023 MotoGP Valencian Grand Prix
6	ITA	Gilera*	35	1949–1965, 1967	1949 500cc Dutch TT	1963 500cc Dutch TT
7	UK	Norton*	21	1949–1972	1949 500cc Isle of Man TT	1969 500cc Yugoslavian Grand Prix
8	AUT	KTM	7	2016–	2020 MotoGP Czech Republic Grand Prix	2022 MotoGP Thailand Grand Prix
9	UK	AJS*	5	1949–1962, 1964–1966	1949 500cc Swiss Grand Prix	1952 500cc Swiss Grand Prix
10	ITA	Moto Guzzi	3	1949–1958, 1962–1963, 1965, 1967, 1969–1970	1951 500cc Swiss Grand Prix	1955 500cc Ulster Grand Prix
	UK	Matchless	3	1952–1974	1961 500cc Argentine Grand Prix	1962 500cc Argentine Grand Prix
	ITA	Cagiva	3	1980–1995	1992 500cc Hungarian Grand Prix	1994 500cc Australian Grand Prix
	ITA	Aprilia	3	1994–1997, 1999–2000, 2002–2004, 2015–	2022 MotoGP Argentine Grand Prix	2023 MotoGP Catalan Grand Prix
14	JPN	Kawasaki	2	1969–1975, 1980–1982, 2002–2009	1971 500cc Spanish Grand Prix	1975 500cc Isle of Man TT
15	CZE	Jawa	1	1962–1966, 1968–1970, 1972	1966 500cc East German Grand Prix	1966 500cc East German Grand Prix
	ITA	Linto	1	1968–1972	1969 500cc Nations Grand Prix	1969 500cc Nations Grand Prix
	GER	König	1	1971–1976	1973 500cc Yugoslavian Grand Prix	1973 500cc Yugoslavian Grand Prix
	ITA	Sanvenero	1	1981–1982	1982 500cc French Grand Prix	1982 500cc French Grand Prix

By nationality

As of the 2023 Valencian Grand Prix

Rank	Country	Wins	Constructor(s)
1	Japan	657	4
2	Italy	272	8
3	United Kingdom	29	3
4	Austria	7	1
5	Czech Republic	1	1
	Germany	1	1