This is a list of Akron Zips football players in the NFL Draft.
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| Year | Round | Pick | Overall | Player | Team | Position |
|---|---|---|---|---|---|---|
| 1941 | 22 | 1 | 203 | Mike Fernella | Philadelphia Eagles | T |
| 1967 | 13 | 23 | 338 | Al Kerkian | Dallas Cowboys | DE |
| 16 | 18 | 411 | Don Williams | Cleveland Browns | WR | |
| 1968 | 12 | 7 | 307 | Paul Paxton | Miami Dolphins | T |
| 1969 | 11 | 25 | 285 | Ken Delaney | Baltimore Colts | T |
| 1987 | 7 | 10 | 178 | Chris Kelly | Pittsburgh Steelers | TE |
| 1989 | 10 | 23 | 274 | John Buddenberg | Cleveland Browns | T |
| 1993 | 8 | 28 | 224 | Daron Alcorn | Tampa Bay Buccaneers | K |
| 1997 | 3 | 13 | 73 | Jason Taylor | Miami Dolphins | DE |
| 2001 | 3 | 22 | 84 | Dwight Smith | Tampa Bay Buccaneers | DB |
| 2002 | 5 | 16 | 151 | Jake Schifino | Tennessee Titans | WR |
| 2005 | 3 | 3 | 67 | Charlie Frye | Cleveland Browns | QB |
| 2006 | 4 | 33 | 130 | Domenik Hixon | Denver Broncos | WR |
| 2007 | 3 | 25 | 88 | Andy Alleman | New Orleans Saints | G |
| 2008 | 4 | 15 | 114 | Reggie Corner | Buffalo Bills | DB |
| 2016 | 5 | 38 | 175 | Jatavis Brown | San Diego Chargers | LB |