In the town of Wartwood, the amphibian townsfolk are in an uproar over a supposed beast. Sprig Plantar, the grandson of Hop Pop and older brother of Polly, becomes determined to capture the beast, only to learn that it is a human teenage girl named Anne Boonchuy who was transported there by a mysterious music box. He ends up befriending her, but the townsfolk plan to kill her. A giant praying mantis interrupts their attempt and Anne helps the people defeat it. Sprig convinces the reluctant townsfolk to help Anne find a way home and Hop Pop reluctantly allows Anne to stay with them.

Anne accidentally breaks Hop Pop's favorite cane. Worried that she will get kicked out, she, Sprig, and Polly visit the town wood-smith Leopold Loggle so he can fix it. He tells them that he cannot, but directs them to the Doom Tree which is the cane's source. The tree ends up being a giant stick bug and they fight it before scaring it away with termites while also messing up Loggle's store. Anne comes clean to Hop Pop about breaking his cane and prepares to leave, but Hop Pop tells her that she can stay and simply wanted her to respect him. He simply has her do the dishes for the incident.

To win the town's annual potluck and avoid the "Shame Cage" again, Anne leads the family on a quest to make pizza. After gathering most of the ingredients, they go to get tomatoes, which can only be obtained from a giant carnivorous tomato plant. They get swallowed by the plant and lose the ingredients in their stomach. Anne apologizes for putting the family in danger as she just wanted to help them win for once. Through Hop Pop's old cookbook, they find that they can eat their way out of the plant. Though the family loses again, their dish still turns out better than before.

Anne and Sprig rescue a small cat-like caterpillar who resembles Anne's pet cat back at home, Domino. Naming the creature Domino II, Anne sneaks him into the house as Hop Pop has a firm stance against having pets. Domino II ends up being a hassle to own, but Anne continues to keep him. Eventually, Domino II makes a cocoon and Hop Pop finds out, telling them that it is a Coastal Killapillar. Domino II emerges and attacks the family, forcing Anne to finally get rid of the creature. Sprig later compares the incident to adopting her into their family and gives Anne a stuffed doll version of Domino II.

Hop Pop allows Anne to ride Bessie, the family snail, but needs her to read Bessie's history before doing so. Anne thinks it is better to ride by experience, so she and Sprig take Bessie for a joy ride. They get stuck in the forest and Sprig rides with Mrs. Croaker to get Hop Pop while Anne reads Bessie's history to pass the time. Anne gets attacked by savage hedgehogs, but having learned patience, Anne manages to get Bessie to escape, picks up Sprig from a wily Croaker, and heads for home so Anne can finish the book. Upon finishing, Hop Pop allows Anne to drive Bessie whenever she wants.

Seeing that Hop Pop does not take any suggestions from anyone, Sprig challenges Hop Pop for the control of the farm. Sprig surprisingly defeats Hop Pop and starts to take all suggestions. Seeing that the farm is falling apart and that Sprig is mad with power, the girls get Hop Pop, who was among beetles in the cemetery and has learned humility. Hop Pop challenges Sprig to a rematch, during which he promises Sprig that he will consider some of the suggestions. Sprig forfeits the match, and everything goes back to normal. Hop Pop is later delivered some suggestions, but he rejects some of them.

Anne and Sprig run into Ivy Sundew, Sprig's childhood friend. Believing that Sprig possibly likes her, Anne, Hop Pop, and Ivy's mother Felicia attempt to set them up at the Firefly Formal forcing them to perform a special dance. However, they have no interest in wanting to date each other, so they leave the dance together and watch fireflies. Not wanting to let the courtship be ruined, Anne and the others follow the two kids only to get captured by a couple of giant love doves. Sprig and Ivy then head off to rescue them. After the rescue, Sprig comes to realize that he is in love with Ivy.

To get out of working in the rain, Anne pretends to be sick. Unfortunately, this means that the Plantars get sick, so Anne decides to help them out. Shortly, the Plantars begin to develop red leg disease which could be fatal. Feeling guilty, Anne takes the Plantars to the highest mountain to bathe in the healing waters to be cured. When this seemingly does not work, Anne admits that she lied about being sick, but the Plantars forgive her. It turns out that Anne simply fed them red mushrooms; the side effects of which turn the skin red. Anne happily, and comically, cries that the Plantars will be fine.

While at Stumpy's Diner, Anne overhears obnoxious food critic Albus Duckweed complain about the food. Having worked in a restaurant all her life, Anne decides to help an unenthusiastic Stumpy change the overall look and menu of his diner. Going with a Thai theme, the makeover is a huge success, but Duckweed is still unimpressed and wants something special. They decide to cook Kraken, but it comes to life and starts attacking everyone. They defeat it and Duckweed changes his mind; finding the experience wonderful. Stumpy takes to the new look and tells Anne her parents would be proud.

Anne is disappointed that nobody in Wartwood respects her. When she meets the foot soldiers of Toad Tower, Anne impresses them with her skills and they make her deputy after telling her that they have come to collect the tax. Sprig becomes jealous but discovers that Toadstool has been squirreling away the tax for himself. Anne begins to regret working with the toads due to their brute force and turns on them. When Sprig outs Toadstool's treachery, the townsfolk turn on Toadstool and the Toads. The Toads decide to tell their captain about Anne while the townspeople praise her heroics.

Wartwood celebrates Grubhog Day with an annual festival. Hop Pop forces Sprig to volunteer to watch over the grubhog, but that means having to miss the fair. Anne suggests bringing the grubhog with them on the rides, but while riding the coaster, a buzzard makes off with it. Anne and Sprig make a sock puppet variant, but Sprig comes clean when they try to cut it open. Hop Pop admits that he put too much pressure on him. While the townsfolk are disappointed that the grubhog is missing, they like the puppet show they put on and decide to make that their annual tradition from now on.

After the town theater troop gets eaten, Anne decides to show everyone in town the movie Love Choice. Everyone immediately becomes split due to the protagonists' two differing love interests and two factions are made with Sprig and Polly leading their opposing sides. The whole town goes to war with Anne and Hop Pop trying to get Sprig and Polly to end their feud. When Polly's life ends up being in danger, Sprig "sacrifices" himself when he realizes that needs to protect his sister, and everything goes back to normal. To prevent another incident, Anne decides to show the arthouse film My Dinner with Anders.

Sprig finds a blue moon shell that he hopes to give to Ivy on her birthday. However, the shell gets stolen so he and Anne play cops and try and find the culprit. After a series of dead ends, they encounter a southern tusk frog named Gunther who is sweet and nice, but when angered turns into a giant monster. Realizing that they have been causing too much trouble, Sprig apologizes and Gunther forgives them. When they return home, they discover that Ivy had taken the shell to clean it. Sprig decides to give it to her early, but she tells him to keep it so that she knows where his house is.

Hiber Day is coming to freeze all the frogs, and when that happens someone goes missing never to be seen again. Anne decides to protect the frogs during the freeze, but grows bored and awakens an inebriated Sprig to have fun. Polly ends up being the one that gets taken by a giant albino weasel and Anne and Sprig chase it back to its cavern. Anne discovers that it was just trying to feed its babies, so she makes an omelet for them in exchange for getting Polly back. As Hiber Day ends, Anne fesses up to what occurred, but Hop Pop tells her that her confessing was very responsible of her.

After Anne and the Plantars return from the archives, Bessie suddenly breaks down when it begins to rain. They stay at the Dandy Lion Inn, run by a kind bullfrog couple named Teddy and Martha. Polly, who will not admit to being afraid, tries to sleep by herself, only to discover that not only is her family gone, but that the bullfrogs are cannibals. She rescues her family and Anne mixes their stash of vinegar and baking soda, causing the inn to explode just as they escape with Bessie. Hop Pop congratulates Polly on her independence, but Polly decides to sleep with Hop Pop for the night.

Sprig looks forward to the family fishing trip and spending time with Hop Pop. However, Hop Pop's girlfriend Sylvia comes along, and Sprig gets jealous of her and tries to get rid of her while Anne tries to hang glide. Just as Sprig gets rid of Sylvia, Hop Pop tells him that Sylvia told him to spend time with him. Sylvia just so happens to be in harm's way by a giant crab and Sprig rescues her using Anne's hang glider, much to her annoyance. He finally admits that he was jealous of Sylvia, but is now glad that she has him. Polly also hang glides better than Anne who wants to eat the crab.

Sprig is scared of Maddie, his fiancé, so Anne helps him break up with her. Afterward, Sprig and Anne wake up to find that they are a furball and a bird, respectively. They believe that Maddie cursed them, but she denies any wrongdoing. She helps find the true culprit, the candy maker Barry who cursed them due to a petty mishap. A fight breaks out with Maddie the victor and Barry changes Anne and Sprig back to normal while also getting a large supply of candy in return. Sprig apologizes for judging Maddie and they decide to simply be friends from now on, though Maddie is still creepy about it.

The town is celebrating Harvest Day, and part of the celebration is the Big Bugball Game. Farmers and Townies always go up against each other with the former usually losing. When Hop Pop sees that Anne is a natural, he has her join the team. She ends up being a handful, but over time learns to be a team player by taking part in trust exercises. The Farmers are doing well, resulting in the Townies blinding Anne. Using her trust exercises, Anne manages to play and Sprig makes the winning dunk, making it the first time the Farmers win. The Townies have to wear an itchy turkey costume for their loss.

Fed up with the children disobeying him, Hop Pop buys a potion from the mysterious Apothecary Gary which when used on someone, makes them more compliable. When he sees that it works, albeit in an unsettling manner, he uses it again, but it turns them into mushroom zombies. Gary reveals that he is a mushroom possessing a frog and that he has zombified all the Wartwood citizens. Hop Pop frees Bessie who proceeds to devour the mushrooms, turning everyone to normal and defeating Gary. Hop Pop apologizes for trying to control the kids while the kids agree to be more respectful to Hop Pop.

Anne and the Plantars make preparations to go to Newtopia to get answers to the music box. Hop Pop hires Chuck to house sit for them, but Anne thinks he is incompetent and buys a potion from Loggle. She uses it on the plants to fortify the house, but it creates a vegetable monster that destroys it and Anne ends up defeating it. Hop Pop tells her that she does not need to worry as Chuck is revealed to be an expert builder and rebuilds the house in seconds. Hop Pop claims that he has left the music box with his contacts and Anne and the Plantars begin their journey to the city of Newtopia.

The family arrives at Bittyburg, a literal small town where its tiny citizens are being forced to pay the ruthless outlaw Judro Hasselback. Hop Pop fends him off, but he returns with the rest of his family led by Mama Hasselback. The Plantars and Anne are forced to flee. Hop Pop suddenly has an epiphany and decides to return to the town to save the civilians. They come in with a plan that works, but when Hop Pop is injured, the citizens of Bittyburg suddenly produce sharp teeth and attack the Hasselbacks, allowing the family to leave. Elsewhere, the robot continues to follow in the desert.

Polly begins acting out and becoming a nuisance to the family. They decide to stop by a rest stop, during which Polly switches places with a pink stone in the hopes of freaking them out. Instead, they drive off, leaving Polly to sulk with the other truckers including Soggy Joe. She learns that the pink rock is an egg belonging to a roc and she and Joe race after the wagon just as the family notices something is off. Polly uses her ability to conduct electricity and defeats the roc and apologizes for her behavior while the rest of the family admits that they miss home and understand Polly's plight.

Halfway to Newtopia, Sprig and Polly will not stop bickering, so Hop Pop drops them off at Quarreler's Pass, a split road to let travelers vent their frustrations. The two continue to fight until they end up in a cave belonging to a two-headed olm named Lysil and Angwin who intends to devour. They finally put their differences aside and use their vocal mimicry to get the olm to fight with itself and escape where they reunite with Hop Pop and Anne. The whole time, Anne had been listening to Hop Pop's non-stop advice on how to get a boyfriend. After listening for far too long, Anne comically kicks Hop Pop off the fwagon (family wagon).

The family makes a stop in Ribbitvale, a highly affluent, upper-class town. They discover that One-Eyed Wally is there and is the son of Wigbert Ribbiton, one of the richest frogs in Amphibia. Wally does not want his father to find out about his double life in Wartwood, but Anne makes it known, angering his father. Wally challenges him to a game of beast polo for his freedom and wins. Despite this, he wants his dad to accept him for who he is as he still wants to associate as a Ribbiton. His father finally accepts him before revealing that he shares some of his son's quirks from Wartwood.

The family stop by Stony Gulch where the residents marvel at Anne's appearance. This leads them to the wax museum run by the Curator. When Anne spots a CD player, the Curator promises to give it to her if she does a show for one night. However, he instead reveals his sinister plan to coat her in wax and be a permanent exhibit. The Plantars catch on and try to rescue her by melting the wax off the rest of the exhibits that come to life and get their revenge on the Curator by presumably killing him. Anne apologizes for being reckless while Sprig reveals that he snagged the CD player for her.

Marcy picks up on a "puzzlegram", a telegram composed of puzzles from the king. Anne attempts to show Sprig that she is smart by solving them, but Marcy figures them out better. Instead, Anne ends up helping and befriending various citizens all over Newtopia. Eventually, Anne's actions get the group in trouble, but they are saved by the people Anne helped. Anne admits that she is jealous of Marcy's intelligence, but Marcy admits that Anne has better social skills and they make up. Anne figures out the last clue, which reveals that the message is "Bring Me the Plantars" and go meet the king.

Anne and Polly break away from a tour group so that they can experience the inner streets of Newtopia for themselves by pretending to be sick while Hop Pop keeps Sprig handcuffed to him so that he, ironically, does not cause any trouble. Anne and Polly traverse the streets only to cause trouble wherever they go. Eventually, a mob chases them back to the tour bus and they use a spicy burrito to deter the crowd and continue on their way to the cheese museum. Meanwhile, Marcy and King Andrias are doing research when Marcy discovers a secret library while Andrias follows her smugly.

While the kids wait in line at an arcade, Hop Pop goes to meet Sal, who runs a sandwich shop. He arrives to see that the place looks ransacked and, donning a hat, begins to act as if he is in a detective noir. Hop Pop is convinced that someone had stolen Sal's sauce recipe and is now selling it. After various mishaps, he locates the source in a factory, only to find that Sal is the one selling the sauce. He admits that the sandwich business was not doing well, so he mass-produced the sauce instead. He tells Hop Pop to embrace change and he returns to the kids who failed to get into the arcade.

Marcy invites Anne, Sprig, and Polly for a sleepover and is warned by Lady Olivia to not go into the basement. They decide to do a scare dare challenge with whoever chickens out has to have their name put in the Book of Losers. In the basement, they encounter strange jellyfish ghost-like creatures and see other numerous oddities. They use mirrors to deter the ghosts and stay up all night long. In the morning, all four put their names in the Book of Losers with Anne and Marcy having put their names in numerous times and agreeing to make up with Sasha. Lady Olivia calls them to Andrias.

Wanting to be home quicker, Sprig and Polly decide to drive the fwagon in the night while Anne and Hop Pop sleep. They come across a terrifying hitchhiker and try to avoid him but he continues to appear and manages to get on the fwagon. As morning rises, the hitchhiker disappears and Sprig and Polly discover a statue of him, who turned out to be the ghost of a helpful guide named Zechariah Nettles. Anne and Hop Pop wake up and find the two frog kids in a tired daze. While at first angry, they let them sleep so that they can drive the rest of the way home. Down the road, the robot continues to follow them.

In this Halloween special, the Plantars stay inside during a blue moon so they won't turn into beasts. To pass the time, they tell spooky stories.

• "Phone-Mo": Anne, renamed Anna, is told about an animal video by her friends that traps people within the video's dimension. She watches it and finds that her friends are trapped in it. The Screen Fiend comes out of the video as a monster to take her. Finding that it is weak against harsh criticism, Anna dislikes the video, defeats the monster, and saves her friends, but monster eggs are left behind.

• "Dead End": A young Hop Pop works as a wagon driver picking up his next customer Mr. Littlepot. After a few stops, Hop Pop realizes that Littlepot is death personified and the next stop is at his farm. However, instead of Hop Pop, Littlepot takes his hair to cover his baldness and leaves while Hop Pop cries over the loss of his long and luxurious hair.

• "Skin Deep": Sprig and Ivy are playing bugball until they lose the ball and go looking for it. They find the ball in an old house that belongs to a skin-wearing monster called the Seamstress. Sprig rips her mask off, revealing her to be a glass frog who uses her skin cloth to cover herself. Sprig and Ivy beat the monster and escape.

After Sprig and Ivy prank the family, Polly, wanting a spooky story to tell since most of her stories were all experiences the family had, looks at the blue moon to turn into a beast. Nothing happens at first and the blue moon legend appears to be false. That is until Polly turns into a wolf-beast, which freaks out the Plantars.

Ivy is trying to hang out with Sprig, but Felicia is constantly making her do her chores in such a specific and perfect manner. Fed up with Felicia's overbearingness, she decides to run away, something Sprig tries to dissuade her from. They run into Anne and Polly, who were training in Muay Thai. Felicia catches up with Ivy, and agrees to end the tea lessons if she can defeat her once in a three-round match, where Felicia reveals herself as a competent fighter. By letting Ivy win, Felicia reveals that she has been training her for the day that they eventually adventure together, and the two reconcile.

Marcy is disappointed to learn that the people of Wartwood do not like her. Despite Anne telling her that it will take time, Marcy decides to "fix" things in their town which makes them happy, but they still do not like her. Mayor Toadstool offers some ideas to improve the town, but the heavy load causes Wartwood to sink into the swamp it was built on top of. Marcy gets rid of the excess and saves the town. Everyone scolds Marcy for being inconsiderate, but they tell her that she was just like Anne when she first came to Wartwood. Marcy makes it up by building the town as it was originally.

Mayor Toadstool begins to like being helpful to the people of Wartwood, but is approached by Newtopia emissary Jacinda who offers him to lead South Toad Tower and adds that turning it down will result in his imprisonment. With Anne and the Plantars' help, he tries to look incompetent, but to no avail. Bog and the rest of the Grime's former Toad warriors attack Wartwood, but Toadstool defends the town and saves the day. Instead, Jacinda decides to make Bog the new leader after deeming Toadstool as "too soft" and he is allowed to stay in Wartwood much to everyone's casual acceptance.

Anne, Marcy and the Plantars arrive in a frozen tundra where they run into Valeriana who claims that she can take them to the second temple. However, she continuously belittles Anne due to her selfless acts to help her friends. After insulting her, Valeriana takes Anne to a spire and recalls her misdeeds. Once again, Anne acts selfless and Valeriana reveals that it was all a test and rewards her with recharging the blue gem on the box. However, Anne leaves before it can finish charging when she believes her friends are in danger. Upon heading home, the blue gem begins to flicker.

While Anne, Marcy and the Plantars pack for the last temple, Bessie is placed in charge of looking after MicroAngelo who continuously gets into trouble. Meanwhile, Marcy hires a fashion expert from Newtopia named Bernardo to find the perfect armor for Anne. After a series of mishaps, Bessie rescues MicroAngelo from a giant bat creature while simultaneously putting out a fire that was almost going to blow everyone up. Anne eventually settles on a "minimalist" armor chest plate so that she can see herself, while Bessie and MicroAngelo form a close bond with each other.

Anne, Marcy and the Plantars invite Sasha and Grime over for dinner to bury the hatchet. While things are calm at first, everyone starts bringing up past conflicts. Unable to contain herself, Sasha lashes out at Anne and Marcy for trying to change her. A cake Grime brought turns into a deadly challenge that forces the girls to save everyone. Afterwards, Anne tells Sasha that while she knows it is difficult for her to change, she needs to accept that she and Marcy have done, then Sasha apologizes.

In a flashback to the day of Anne's birthday, Marcy is upset when her parents announce they are moving and inspired by a book, discovers the Calamity Box, and suggests getting it for Anne for her birthday. In the present, the girls, the Plantars, and Grime arrive at Newtopia, but Sasha and Grime unveil their plan to take over the kingdom. Upset that she was betrayed by her friend again, Anne rallies everyone to take back the kingdom, during which Sasha and Grime discover that Andrias has sinister motivations. They are successful, but Andrias reveals that he intends to conquer other worlds using the box and Marcy admits to knowledge of the box's power. A fight breaks out, during which Frobo is destroyed, much to Polly's chargin. Polly grows legs and takes back the music box, but is forced to return by Andrias after he threatens to drop Sprig out of the tower. However, Andrias decides to drop Sprig anyways, with Marcy saving him. Anne unleashes her inert blue gem power. Marcy opens the portal home but is stabbed by Andrias just as Anne and the Plantars enter and arrive in Los Angeles.

Realizing that the Plantars cannot restrain themselves in her world, Anne takes them to the mall and challenges Polly to not lose her temper, Sprig to not touch anything, and Hop Pop to not fall for "free" things. Anne gets distracted by her talkative friend Gabby, resulting in the Plantars getting in trouble. Anne rescues them and apologizes for throwing them into the world without planning as they had done for her, but the Plantars point out that she made the same mistakes in Amphibia. Nevertheless, they promise to be more compliant and listen to her when she warns them.

Wanting to be accepted as a Boonchuy as Anne had been accepted as a Plantar, Sprig joins them to work at their restaurant Thai Go. Their biggest customer Ned does not realize that his dream to expand their business by opening a food truck is hurting it, so Sprig tries to sabotage him. He ends up making things worse and he and Anne find themselves trying to maneuver Ned's out-of-control food truck. Sprig takes responsibility for the events which convinces Ned to cease his dream but gets hired as a delivery boy. Mrs. Boonchuy scolds Sprig which ironically makes him happy as this means he is a Boonchuy now.

Obsessed with studying the multiverse, Anne and the Plantars head to the museum and find an ancient jar of Amphibian origin. They meet the curator Dr. Jan who offers to talk about it, but a sleep-deprived Anne, in a paranoid delusion, turns her down. They resolve to steal the jar at night and end up running into the Cloak-Bot where a fight breaks out. Dr. Jan and a couple of security guards spot the Cloak-Bot, forcing it to flee. Despite seeing the Plantars, Dr. Jan protects them and learns the jar's importance. She tells Anne to get some sleep and in the morning, she discovers a hidden message using a black light.

Despite being told not to, Polly tries to fix Frobo on her own and gets help from an internet duo named Ally and Jess (The IT Gals). She faces chats with them and they give her the help she needs, but are concerned with her plans. When Anne, Hop Pop, and Sprig find out what she is doing and reprimand her for it, Polly angrily activates Frobo and puts herself in danger. Frobo remembers who he is and saves Polly, but they crash land in the backyard and he is reduced to a head again, though he is still active. Ally and Jess arrive and are impressed with Polly's skills and decide to help her fix Frobo.

As Anne takes the Plantars to the movies, the enigmatic Mr. X begins to snoop around for them. Mr. and Mrs. Boonchuy quickly discover this when he comes asking around for them and tries to warn Anne. When Mr. X has every corner of the cinema covered, Anne and the Plantars hastily try to run and hide from them. Mr. and Mrs. Boonchuy offer help to Anne who continues to refuse it. Eventually, the parents manage to rescue them and Anne admits that she underestimated them. Mr. X vows to catch the Plantars next time. The Boonchuys reveal that they planted a tracker onto Hop Pop.

After watching a superhero movie called Tarantu-Lad, Sprig decides to use his abilities to become the superhero Frog-Man. His actions earned him the ire of junkyard owner/self-proclaimed "neighborhood safety supervisor" Robert Otto, but the admiration of the people of Los Angeles including Robert's granddaughter Molly Jo. Robert discovers Cloak-Bot's arm in his junkyard and becomes a villain to get revenge on Sprig. Their battle destroys the streets and Molly Jo chastises them. Realizing that he was simply seeking attention, Sprig, and Robert clean the city. Afterward, Sprig gives up being a hero.

Upon arriving in Hollywood, Hop Pop finds himself auditioning for a commercial and gets the part, despite another man named Humphrey Westwood giving up his chance for it. The commercial becomes a hit which gets the attention of Mr. X. After getting offered a big part in a movie, Hop Pop takes off with Mr. X in pursuit and Anne, Sprig, and Polly also after him. However, Hop Pop learns that Humphrey is a janitor who has been waiting for his big break and gives up his role to him. Mr. X is humiliated once again and Hop Pop returns home with the intent to pursue a career in directing instead.

Anne and the Plantars discover that Wartwood has become the home base for the resistance with Sasha leading them. However, Sasha decides to hand command over to Anne despite her reluctance. Anne turns out to be terrible at leading, especially when they have to take down one of King Andrias' factories. Sasha finally admits that she is afraid of ruining everything as she did with their friendship. Anne puts herself in harm's way so that Sasha can regain her confidence and rescue everyone from a giant snake. Anne hands command back over to Sasha but agree to co-lead with her to make her comfortable.

Sasha puts together a team to help take down a Marauders camp, their leader being Barry. They get ambushed; getting everyone captured, sans Sasha and Anne who wait and spar with each other. Toadie has trouble breaking out of his comfort zone and botches a plan to escape which results in Mrs. Croaker getting knocked out. After being pushed too far, Toadie finally leads the team to break out, destroying the camp and getting their supplies back. Sasha tells Anne that she does care about the Wartwood citizens and that she needs to trust her judgment even when she makes difficult decisions.

Anne, Sasha, and the Plantars meet Mother Olm who has information on the prophecy, but cannot remember. The kids go into her head to rub cream on her brain while Hop Pop waits outside with Mother Olm who gives him encouraging advice on being old. The kids are attacked by batsquitos and get trapped in the nose. Hop Pop gets Mother Olm to sneeze them out, but she still cannot remember. Luckily, she wrote down the prophecy which says that "three stars" will burn brightly, implying that Sasha and Marcy also have superpowers similar to Anne and will help them regain them.

Anne, Loggle, and the Plantars find themselves in a village called Gardenton where all the residents love horticulture, much to Hop Pop's delight. However, they discover too late that their leader is their old enemy Apothecary Gary, now using Jeremy the Beetle as his host, and with the villagers willingly under his control. Gardenton is attacked by Andrias' forces and the heroes save the village. Hop Pop convinces Gary that they have a lot in common and gets him to help fight alongside the resistance while also revealing that there may be another fungal creature like him.

As some toads and newts are working for Andrias, Anne and Sprig are reunited with Tritonio who leads a band of neutral thieves who steal from Andrias, but are unaligned with the rebellion. When his team is captured, he bails on them due to his harsh upbringing on the streets. Words of encouragement lead him to change his mind and he rescues his thieves from a judge-themed Frobot and joins the rebellion. Back at base, the group finds a hidden room that contains a red envelope with no writing. While disappointed, Sprig takes extra precaution and pockets the letter before leaving.

Anne is shocked to learn that the frogs, newts, and toads do not get along, despite her hard work of getting them to fight against Andrias. She has Beatrix, leading the toads, and Tritonio, leading the newts, come and work with the frogs via team-building exercises, but these all end in disaster. Fed up with everyone, Anne uses her powers to set everyone straight and the three armies finally formulate a plan. Mother Olm arrives to tell everyone that King Andrias has decided to start his invasion of Earth that very night; leading everyone to prepare for the final battle.

Anne and Sprig play a new video game on her phone resembling their adventures. Hop Pop later tells them to clean the spiders out of the bathroom to lure them away so he can play the game.