The Copa Sudamericana is an annual football cup competition organized by CONMEBOL since 2002 for football club in South American.

Over the past nine tournaments, twelve players have been the top scorers of the Copa Sudamericana. No person has ever repeated as the top scorers. Argentine players have been the top scorers four times, the most of any other country. Pierre Webó is the only non-South American to be a top scorer. The all-time top scorer is Eduardo Vargas, who scored all eleven of his goals in 2011.

By tournament

Season	Player	Nationality	Club	Goals
2002	Rodrigo Astudillo	Argentina	San Lorenzo	4
	Gonzalo Galindo	Bolivia	Bolívar
	Pierre Webó	Cameroon	Nacional
2003	Germán Carty	Peru	Cienciano	6
2004	Horacio Chiorazzo	Argentina	Bolívar	5
2005	Bruno Marioni	Argentina	UNAM	7
2006	Humberto Suazo	Chile	Colo-Colo	10
2007	Ricardo Ciciliano	Colombia	Millonarios	6
2008	Alex	Brazil	Internacional	5
	Nilmar	Brazil	Internacional
2009	Claudio Bieler	Argentina	LDU Quito	8
2010	Rafael Moura	Brazil	Goiás	8
2011	Eduardo Vargas	Chile	Universidad de Chile	11
2012	Jonathan Fabbro	Paraguay	Cerro Porteño	5
	Carlos Núñez	Uruguay	Liverpool
	Fábio Renato	Brazil	LDU Loja
	Wason Rentería	Colombia	Millonarios
	Michael Ríos	Chile	Universidad Católica
2013	Enner Valencia	Ecuador	Emelec	5
2014	Miler Bolaños	Ecuador	Emelec	5
	Andrés Vilches	Chile	Huachipato
2015	Ramón Ábila	Argentina	Huracán	5
	Miler Bolaños	Ecuador	Emelec
	Wilson Morelo	Colombia	Santa Fe
	José Ariel Núñez	Paraguay	Olimpia
2016	Miguel Borja	Colombia	Atlético Nacional	6
	Cecilio Domínguez	Paraguay	Cerro Porteño
2017	Jhon Cifuente	Ecuador	Universidad Católica	5
	Luis Miguel Rodríguez	Argentina	Atlético Tucumán
	Felipe Vizeu	Brazil	Flamengo
2018	Nicolás Benedetti	Colombia	Deportivo Cali	5
	Pablo	Brazil	Athletico Paranaense
2019	Silvio Romero	Argentina	Independiente	5
2020	Braian Romero	Argentina	Defensa y Justicia	10
2021	Agustín Álvarez	Uruguay	Peñarol	10
2022	Bernardo Cuesta	Argentina	Melgar	8
2023	Gonzalo Mastriani	Uruguay	América Mineiro	9