The following is a list of notable people associated with Jacksonville State University, located in the American city of Jacksonville, Alabama.

Politics

• Ademola Adeleke - former Nigerian Senator and current Governor of Osun State in Nigeria
• Jim Folsom Jr. - former governor and lieutenant governor from Alabama
• Harlan Mathews - former Democratic U.S. Senator from Tennessee
• Elvin McCary - Republican politician from Anniston
• Hugh D. Merrill - former member of the Alabama House of Representatives
• Mike D. Rogers - Republican U.S. Representative from Alabama's 3rd congressional district

Science and Technology

• JoAnn H. Morgan - aerospace engineer, first female engineer at NASA John F. Kennedy Space Center

Religion

• F. Richard Spencer - Roman Catholic bishop
• Dr. Ronnie Reid - Worship Pastor

Writers

• Rick Bragg - Pulitzer Prize–winning writer. Author of Ava's Man and All Over but the Shoutin.
• James Joyner - Well-known blogger and political scientist.
• Robert Stacy McCain - author of Donkey Cons and assistant national editor of the Washington Times.

Athletics

• Rudy Abbott - Legendary baseball coach with over 1,000 career wins, Member of Alabama Sports Hall of Fame
• Mohamed Abu Arisha (born 1997) - Israeli basketball player for Hapoel Be'er Sheva of the Israeli Basketball Premier League and the Israeli national basketball team
• Jesse Baker - former National Football League player with the Houston Oilers.
• Dieter Brock - former National Football League player and Canadian Football League MVP quarterback, member of the Canadian Football Hall of Fame^[1]
• Amy Crawford - former WCW Entertainer
• Christian Cunningham (born 1997) - basketball player in the Israeli Basketball Premier League
• Todd Cunningham - professional Major League Baseball outfielder in the Los Angeles Angels of Anaheim organization
• Eric Davis - NFL defensive back San Francisco 49ers, Carolina Panthers and Detroit Lions
• Donovan Hand - MLB pitcher, Milwaukee Brewers
• Walt Harris (fighter) - former basketball player, current mixed martial artist for the UFC^[2]
• Delvin Hughley - former American football defensive back for the Baltimore Ravens and Denver Broncos of the National Football League and the Colorado Crush of the Arena Football League
• Todd Jones - Major League Baseball pitcher
• Joe Kines - College football coach
• Shed Long - professional Major League Baseball second baseman for the Seattle Mariners organization
• Darrell Malone - NFL defensive back for Kansas City Chiefs and Miami Dolphins, 1992–1994^[3][4]
• Ashley Martin - athlete who became the first woman to play and score in an NCAA Division I American football game
• Keith McKeller - former National Football League tight end with the Buffalo Bills
• Terry Owens- NFL San Diego Chargers
• Ryan Perrilloux - former NFL quarterback for the New York Giants, Arena Football League New Orleans Voodoo
• Walker Russell, Jr. - NBA player for the Detroit Pistons
• Jason Seguine - Professional wrestler (as Buck Quartermain) and football player
• Matt Wallace - Professional golfer on the PGA Tour and DP World Tour, winner of the 2023 Corales Puntacana Championship.
• Danny Willett - Professional golfer on the European Tour, winner of the 2016 Masters Tournament
• Mark Word - former National Football League defensive end who played for the Kansas City Chiefs & Cleveland Browns
• Alvin Wright - former National Football League nose guard with the Los Angeles Rams

Business

• Keith Creel - CEO of Canadian Pacific Railway

Media and Entertainment

• Rick Burgess and Bill "Bubba" Bussey - radio personalities. Burgess is the son of retired Hall of Fame JSU Football Coach Bill Burgess.^[5][6]
• Catherine Callaway - CNN Tonight news anchor
• John Craton - classical composer
• Cary Guffey - financial planner, Star of the 1977 Steven Spielberg film "Close Encounters of the Third Kind"
• Jamey Johnson - country music artist. Recipient of multiple ACM and CMA Awards. Former mellophone player for the Marching Southerners.
• Mai Martinez - co-anchor at CBS 2 in Chicago
• Randy Owen - lead singer of the record award-winning country music band Alabama. Current member of JSU Board of Trustees.^[7]
• Reynolds Wolf - CNN meteorologist and reporter
• Riley Green - country music artist. His song “Single Ladies” caught the attention of record label Big Machine Records. His next single “There was a Girl” reaches #1 on multiple country music charts.

Pageant winners

• Teresa Cheatham - Miss Alabama, 1978; First Runner-up in 1979 Miss America
• Jamie Langley - Miss Alabama, 2007
• Heather Whitestone (McCallum) - Miss America, 1995