This is a list of Long Beach State 49ers football players in the NFL Draft.
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| Year | Round | Pick | Overall | Player | Team | Position |
|---|---|---|---|---|---|---|
| 1962 | 19 | 2 | 254 | Lynn Hoyem | Dallas Cowboys | G-T |
| 1966 | 12 | 3 | 173 | Les Shy | Dallas Cowboys | RB |
| 1967 | 13 | 10 | 178 | Roy Schmidt | Green Bay Packers | G-T |
| 1967 | 9 | 14 | 225 | Steve Newell | San Diego Chargers | WR |
| 1968 | 9 | 1 | 220 | Phil Johnson | Cincinnati Bengals | DB |
| 1971 | 1 | 13 | 13 | Leon Burns | San Diego Chargers | RB |
| 1971 | 6 | 16 | 146 | Billy Parks | San Diego Chargers | WR |
| 1972 | 6 | 23 | 153 | John Kahler | Kansas City Chiefs | DE |
| 1972 | 7 | 11 | 167 | Jim Fassel | Chicago Bears | QB |
| 1972 | 11 | 10 | 270 | John Turner | San Diego Chargers | TE |
| 1972 | 12 | 11 | 297 | Jeff Severson | Washington Redskins | DB |
| 1972 | 16 | 17 | 407 | Jim Kirby | Los Angeles Rams | WR |
| 1973 | 3 | 11 | 63 | Terry Metcalf | St. Louis Cardinals | RB-WR |
| 1974 | 14 | 3 | 341 | Greg Bailey | San Diego Chargers | DB |
| 1974 | 15 | 8 | 372 | Leonard Gray | San Francisco 49ers | TE |
| 1975 | 8 | 20 | 202 | Louis Lauriano | St. Louis Cardinals | DB |
| 1976 | 3 | 8 | 68 | Russ Bolinger | Detroit Lions | G-T |
| 1976 | 9 | 16 | 253 | Leanell Jones | Detroit Lions | TE |
| 1976 | 10 | 8 | 273 | Herb Lusk | Philadelphia Eagles | RB |
| 1977 | 4 | 8 | 92 | Mark Bailey | Kansas City Chiefs | RB |
| 1978 | 1 | 24 | 24 | Dan Bunz | San Francisco 49ers | LB |
| 1981 | 3 | 4 | 60 | Ben Rudolph | New York Jets | DT-DE |
| 1981 | 10 | 13 | 261 | Steve Folsom | Miami Dolphins | TE |
| 1982 | 2 | 27 | 55 | Dean Miraldi | Philadelphia Eagles | T-G |
| 1984 | 8 | 20 | 216 | John Puzar | Seattle Seahawks | C |
| 1984 | 9 | 12 | 235 | Mike Horan | Atlanta Falcons | P |
| 1985 | 3 | 11 | 67 | David Howard | Minnesota Vikings | LB |
| 1985 | 3 | 13 | 69 | John Hendy | San Diego Chargers | DB |
| 1985 | 7 | 4 | 170 | Ron Johnson | Seattle Seahawks | WR |
| 1985 | Suppl. | Thomas Fowler | San Diego Chargers | WR | ||
| 1986 | 4 | 17 | 99 | Doug Gaynor | Cincinnati Bengals | QB |
| 1987 | 3 | 10 | 66 | Charles Lockett | Pittsburgh Steelers | WR |
| 1989 | 4 | 3 | 87 | Jeff Graham | Green Bay Packers | QB |
| 1991 | 5 | 27 | 138 | Shawn Wilbourn | Buffalo Bills | DB |
| 1991 | 12 | 15 | 322 | R. J. Kors | Seattle Seahawks | DB |
| 1994 | 7 | 4 | 198 | Jay Walker | New England Patriots | QB |
| 1995 | 6 | 25 | 196 | Terrell Davis | Denver Broncos | RB |