This is an alphabetical list of notable baseball players from the Dominican Republic who have played in Major League Baseball since 1950. Players in bold are still active in MLB, as of 2022.

Since 1956 a large number of baseball players of Dominican origin have played in Major League Baseball in the United States, with the Dominican Republic being the second country in the world after the United States with the most current baseball players in MLB.

A

B

C

D

E

F

G

H

J

K

• Franklyn Kilome

L

M

N

O

P

Q

R

S

T

U

V

W

Y

Z

• Aneurys Zabala