The following were named First Team All-America (by either the American Football Coaches Association, Associated Press, Football Writers Association of America, The Sporting News, Walter Camp Football Foundation, Sports Illustrated, Pro Football Weekly, ESPN, CBS Sports, College Football News, Rivals.com, or Scout.com) while playing American football at Penn State University:
Academic All-Americans
The following were named First Team Academic All-America by the College Sports Information Directors of America (CoSIDA) while playing at Penn State:
- Joe Bellas (1965)[27]
- John Runnells (1965, 1966)[27]
- Rich Buzin (1967)[27]
- Dennis Onkotz (1969)[27]
- Charlie Pittman (1969)[27]
- Dave Joyner (1971)[27]
- Bruce Bannon (1972)[27]
- Mark Markovich (1973)[27]
- Chuck Benjamin (1976)[27]
- Keith Dorney (1978)[27]
- Todd Blackledge (1982)[27]
- Scott Radecic (1982)[27]
- Harry Hamilton (1982, 1983)[27]
- Lance Hamilton (1984, 1985)[27]
- Carmen Masciantonio (1984)[27]
- John Shaffer (1986)[27]
- Jeff Hartings (1994, 1995)[27]
- Tony Pittman (1994)[27]
- Travis Forney (1999)[27]
- Joe Iorio (2002)[27]
- Andrew Guman (2004)[28]
- Paul Posluszny (2005, 2006)[29]
- Tim Shaw (2006)[29]
- Gerald Cadogan (2007, 2008)[30][31]
- Josh Hull (2008, 2009)[31][32]
- Andrew Pitz (2008, 2009)[31][32]
- Mark Rubin (2008)[31]
- Stefen Wisniewski (2008, 2009, 2010)[32][33]
- Chris Colasanti (2010)[33]
- Pete Massaro (2010, 2012)[33][34]
- John Urschel (2012, 2013)[34][35]
- Tyler Yazujian (2016)[27]
- Blake Gillikin (2018, 2019)[27][36]
- Sean Clifford (2020)[37]
- Eric Wilson (2021)[38]