This is a list of airlines of Spain. The list includes only airlines having an Air Operator Certificate issued by the Civil Aviation Authority of Spain.

Scheduled airlines

Airline	IMAGE	IATA	ICAO	Callsign	Commenced operations	Notes
Air Europa Express		UX	OVA	Aeronova	1996/2016	At the beginning of 2016, Air Europa bought Aeronova as a low-cost subsidiary, renaming it Air Europa Express (not to be confused with the already dissolved Air Europa Express (1996)).
Air Europa		UX	AEA	EUROPA	1986
Air Nostrum		YW	ANE	NOSTRUM AIR	1994	Regional franchise of Iberia.
AlbaStar		AP	LAV		2010
Binter Canarias		NT	IBB	BINTER/CANAIR	1989
Canaryfly		PM	CNF		2010
Iberia		IB	IBE	IBERIA	1927	National carrier
Iberia Express		I2	IBS	IBERIAEXPRES	2012	Low-cost branch of Iberia (airline).
LEVEL		IB	IBE	LEVEL	2017
Plus Ultra Líneas Aéreas		PU	PUE	SPANISH	2012
Volotea		V7	VOE	VOLOTEA	2012
Vueling		VY	VLG	VUELING	2004

Charter airlines

Airline	IMAGE	IATA	ICAO	Callsign	Commenced operations	Notes
Evelop Airlines		E9	EVE	EVELOP	2013
Executive Airlines (Spain)			EXU	SACAIR
Gestair		GP	GES	GESTAIR	1977
Gowair Vacation Airlines		G6	GWR	LEMON	2017
Helicópteros del Sureste
Ibertrans Aérea			IBT	IBERTRANS	1991
Inaer		UV	INR		1965
Mayoral Executive Jet			MYO	MAYORAL	1985
Privilege Style			PVG	PRIVILEGE	2003
Swiftair		W3	SWT	SWIFT	1986
Taxijet
Wamos Air		EB	PLM	PULMANTUR	2003	Formerly called Pullmantur Air.
World2fly		2W	WFL	BLUE WORLD	2019

Cargo airlines

Airline	IMAGE	IATA	ICAO	Commenced operations	Notes
Cygnus Airline			RGN	2013