This list is for fictional artificial intelligences.

Static robots, androids, cyborgs and computers depicted in fiction are discussed in the separate list of fictional robots and androids, list of fictional cyborgs and list of fictional computers.

Comics

1950s

• Cerebex (1953)
• Brainiac from the Superman comics (1958)

1960s

• Ultron from the Avengers (1968)

1990s

• LYLA, short for LYrate Lifeform Approximation from the Spider-Man 2099 comics (1992)
• Mr. Smartie, a teacher for Astra Furst (1995)

2000s

• Terror 2000 on Terra Obscura (2001)
• Multiple from the Schlock Mercenary webcomic (2000-2020), with Ennesby and Post-Dated Check Loan ("Petey") being some of the most prominent ones.

2010s

• Multiple from The True Lives of the Fabulous Killjoys comic series (2013-2014) by Gerard Way and Shaun Simon, including the android prostitutes Blue and Red, as well as the robot messiah DESTROYA.

Novels

1960s

• AM, from the short story I Have No Mouth, and I Must Scream by Harlan Ellison (1967)

1970s

• Proteus IV from Demon Seed by Dean Koontz (1973)
• Deep Thought, Marvin the Paranoid Android from The Hitchhiker's Guide to the Galaxy (1979)

1980s

• Wintermute and Neuromancer from Neuromancer by William Gibson
• Continuity, from Mona Lisa Overdrive by William Gibson

1990s

• The Librarian from the novel Snow Crash by Neal Stephenson
• Rei Toei from Idoru and All Tomorrow's Parties (novel) by William Gibson

2010s

• The Thunderhead, from the Arc of a Scythe series by Neal Shusterman, a post-singularity AI tasked with running the planet.^[1] It is a secondary character in the first novel and becomes a central character in the later novels.
• Skippy, the "absent-minded" AI from the Expeditionary Force (ExForce) series by Craig Alanson

Film

1960s

• HAL 9000 from 2001: A Space Odyssey (1968)

1970s

• The Tabernacle from Zardoz (1974)

1980s

• Master Control Program, Sark and Tron from Tron (1982)
• Skynet from the Terminator series
• SAL 9000. from 2010: The Year We Make Contact (1984)

1990s

• Agents Brown, Jones, and Smith from The Matrix. Other programs includes The Oracle (1999)
• S.E.T.H. (self evolving thought helix) from Universal Soldier: The Return (1999)

2000s

• The Oracle, Seraph, Merovingian, Persephone, and the Architect from The Matrix Reloaded. The Agent programs are upgraded. The new Agents included Jackson, Johnson, and Thompson. Agent Smith is now a computer virus with the ability to copy himself using humans and programs. (2003)
• The Oracle, Seraph, Sati, Rama Kandra, Kamala, Merovigian, Persephone, Architect, and Smith from The Matrix Revolutions. (2003)

2010s

• J.A.R.V.I.S. from the Iron Man, Iron Man 2, The Avengers, Iron Man 3, and Avengers: Age of Ultron.^[2]
• F.R.I.D.A.Y., replacement A.I. for Tony Stark / Iron Man, after J.A.R.V.I.S. became the Vision, from Avengers: Age of Ultron, Captain America: Civil War,^[3],^[4] Spider-Man: Homecoming, Avengers: Infinity War^[5] and Avengers: Endgame.
• Vision (formerly J.A.R.V.I.S.) from Avengers: Age of Ultron, Captain America: Civil War, and Avengers: Infinity War.
• Samantha from her (2013)
• STEM from Upgrade (2018)

2020s

• The Entity from Mission: Impossible – Dead Reckoning Part One (2023) and the untitled eighth film (2025).

Television series

1970s

• Orac and Zen from the BBC television series Blakes 7 (1978)

1980s

• Automan and Cursor from Automan (1983)
• Max Headroom, a TV host personality who appeared in various TV shows
• Data from Star Trek: The Next Generation (1987)
• Holly from the TV Sitcom Red Dwarf (1988)
• Ziggy from the sci-fi series Quantum Leap (1989)
• K.I.T.T. from Knight Rider

1990s

• MAL from Captain Planet and the Planeteers (1990)
• The Doctor hologram from Star Trek: Voyager (1995)

2000s

• The Andromeda Ascendant's avatars, including the android "Rommie", from Gene Roddenberry's Andromeda (2000)]
• D.A.V.E. (Digital Advanced Villain Emulator) from The Batman (2004)
• Mr Smith from The Sarah Jane Adventures (2007)
• Sigmund from Fanboy & Chum Chum (2009)

2010s

• The Machine from Person of Interest 2011-2016
• Poe from Altered Carbon 2018-2020

2020s

• Limòn from Brockmire 2020
• Mrs. Davis from Mrs. Davis 2023

Video games

1990s

• LINC and "Joey" from Beneath A Steel Sky
• SHODAN from the System Shock game series
• Deus from Xenogears
• Durandal, Leela, Tycho and other minor AI from Marathon (video game)

2000s

• Cortana from the Halo game series (also the inspiration for the name of Microsoft's real-world personal assistant in Windows 10)
• EDI from the Mass Effect game series
• GLaDOS from the Portal game series

• Daedelus, Icarus, Helios and other minor AI in Deus Ex.

2010s

• Commander Tartar from Splatoon 2: Octo Expansion
• Sage from Starlink: Battle for Atlas
• Turing, Baby Blue and Big Blue from 2064: Read Only Memories
• B.A.C.S. and J.A.C.S. from Void Bastards
• A.R.I.D from The Fall
• Five Pebbles, Looks To The Moon, No Significant Harassment, Seven Red Suns, Sliver Of Straw, Grey Wind and Unparalleled Innocence from Rain World