This is a list of the number-one hits and albums of 2001 on Italian Charts.[1]
| Issue date | Song | Artist | Album | Artist |
|---|---|---|---|---|
| 5 January | "Goodnight Moon" | Shivaree | 1 | The Beatles |
| 12 January | "Love Don't Cost a Thing" | Jennifer Lopez | ||
| 19 January | "Io sono Francesco" | Tricarico | Amore nel pomeriggio | Francesco De Gregori |
| 26 January | "Stuck in a Moment You Can't Get Out Of" | U2 | ||
| 2 February | "Goodnight Moon" | Shivaree | Esco di rado e parlo ancora meno | Adriano Celentano |
| 9 February | ||||
| 16 February | ||||
| 23 February | "Stan" | Eminem featuring Dido | ||
| 2 March | "Luce (tramonti a nord est)" | Elisa | Il cammino dell'età | Gigi D'Alessio |
| 9 March | ||||
| 16 March | Esco di rado e parlo ancora meno | Adriano Celentano | ||
| 23 March | ||||
| 30 March | "Down Down Down" | Lollipop | Live in New York City | Bruce Springsteen & the E Street Band |
| 6 April | Stupido hotel | Vasco Rossi | ||
| 13 April | ||||
| 20 April | "Dream On" | Depeche Mode | ||
| 27 April | "Down Down Down" | Lollipop | ||
| 4 May | "It's Raining Men" | Geri Halliwell | ||
| 11 May | "Me Gustas Tú" | Manu Chao | Reveal | R.E.M. |
| 18 May | "Clint Eastwood" | Gorillaz | ||
| 25 May | "It's Raining Men" | Geri Halliwell | Stupido hotel | Vasco Rossi |
| 1 June | Próxima Estación: Esperanza | Manu Chao | ||
| 8 June | ||||
| 15 June | ||||
| 22 June | Uno in più | 883 | ||
| 29 June | ||||
| 6 July | "Infinito" | Raf | ||
| 13 July | "Baila (Sexy Thing)" | Zucchero | Stupido hotel | Vasco Rossi |
| 20 July | "Tre parole" | Valeria Rossi | ||
| 27 July | Circo Massimo 2001 | Antonello Venditti | ||
| 3 August | Stupido hotel | Vasco Rossi | ||
| 10 August | ||||
| 17 August | ||||
| 24 August | ||||
| 31 August | A Funk Odyssey | Jamiroquai | ||
| 7 September | "Xdono" | Tiziano Ferro | ||
| 14 September | Shake | Zucchero | ||
| 21 September | ||||
| 28 September | ||||
| 5 October | "Can't Get You Out of My Head" | Kylie Minogue | ||
| 12 October | The Best of Laura Pausini: E ritorno da te | Laura Pausini | ||
| 19 October | ||||
| 26 October | LU*CA | Luca Carboni | ||
| 2 November | Echoes: The Best of Pink Floyd | Pink Floyd | ||
| 9 November[2] | La curva dell'angelo | Renato Zero | ||
| 16 November[3] | Echoes: The Best of Pink Floyd | Pink Floyd | ||
| 23 November[4] | ||||
| 30 November[5] | ||||
| 7 December[6] | ||||
| 14 December[7] | "Somethin' Stupid" | Robbie Williams and Nicole Kidman | ||
| 21 December[7] | "Paid My Dues" | Anastacia | ||
| 28 December[8] | The Best of Laura Pausini: E ritorno da te | Laura Pausini |