The following is a list of prominent people who were born in the American state of Maine, live in Maine, or for whom Maine is a significant part of their identity.

A

• Angela Adams (born 1965), designer; born in North Haven
• Paul André Albert (1926–2019), scientist; born in Van Buren
• Tom Allen (born 1945), politician, Congressman (1997–2009); born in Portland
• Adelbert Ames (1835–1933), military officer, politician, Governor of Mississippi (1868–1870; 1874–1876), United States Senator from Mississippi (1870–1874); born in Rockland
• Benjamin Ames (1778–1835), politician, Governor of Maine (1821–1822); lived in Houlton
• Erin Andrews (born 1978), sportscaster, Dancing With the Stars contestant and co-host; born in Lewiston

B

• John Baldacci (born 1955), politician, Governor of Maine (2003–2011), Congressman (1995–2003); born in Bangor, lives in Portland
• Christopher Daniel Barnes (born 1972), actor, voice actor, The Little Mermaid film, Spider-Man television series; born in Portland
• Trevor Bates (born 1993), NFL player; born in Portland
• Leon Leonwood Bean (1872–1967), founder of L.L. Bean Inc., a large private retail company in Freeport
• Corey Beaulieu (born 1983), musician, guitarist in Trivium; born in Brunswick
• Anna Belknap (born 1974), actress, Lindsay Monroe on CSI: NY; born in Damariscotta
• Joan Benoit (born 1957), first women's Olympic marathon champion; born in Cape Elizabeth
• Louisa Dow Benton (1831–1895), linguist, translator; born in Portland
• Jacques Berlinerblau (born 1966), religious scholar, Georgetown University professor; born in Portland
• Carroll Thayer Berry (1886–1978), printmaker, woodcut engraver, painter and photographer; born in New Gloucester
• Nina Blackwood (born 1955), radio and television personality, actor, model; lives in Mid Coast region^[1]
• James G. Blaine (1830–1893), United States Representative, Senator, and Secretary of State, Republican presidential candidate in 1884
• Dennis Blair (born 1947), US Director of National Intelligence (2009–2010), four-star U.S. Navy admiral; born in Kittery
• Cindy Blodgett (born 1975), basketball player and coach; born in Clinton; Attended Lawrence High School and later University of Maine Orono
• Tim Boetsch (born 1981), mixed martial artist; born in Lincolnville
• Gordon Bok (born 1939), folk singer-songwriter; born in Camden
• Milton Bradley (1836–1911), board game manufacturer with the Milton Bradley Company; born in Vienna
• Joseph E. Brennan (born 1934), politician, Governor of Maine (1979–1987), Congressman (1987–1991); born in Portland
• Contessa Brewer (born 1974), news anchor for MSNBC; born in Parsonsfield
• Styles Bridges (1898–1961), politician, Governor of New Hampshire (1935–1937) and U.S. Senator from New Hampshire (1937–1961); born in Pembroke
• James Brooks (1807–1873), Congressman from New York; born in Portland
• Brett Brown (born 1961), head coach and general manager for the Philadelphia 76ers; born in South Portland
• Harry Brown (1917–1986), poet, novelist, screenwriter; born in Portland
• Scott Brown (born 1959), U.S. Senator from Massachusetts (2010–13); born in Kittery
• Ashley Bryan (1923–2022), writer and illustrator; resided in Islesford
• Marisa Butler (born 1994), American model, Singer and Beauty Pageant title holder; Miss Maine USA 2016, Miss World America 2018 and Miss Earth USA 2021
• Brian Butterfield (born 1958), professional baseball coach; born in Bangor

C

• Nik Caner-Medley (born 1983), basketball player; born in Portland
• Al Carbee (1914–2005), outsider artist; born in Portland, lived in Saco
• John Cariani (born 1969), actor, Law & Order; grew up in Presque Isle
• Howie Carr (born 1952), journalist, author, radio talk-show host; born in Portland
• Bill Carrigan (1883–1969), catcher and manager for Boston Red Sox; born in Lewiston
• Rachel Carson (1907–1964), author; lived in Southport
• Walter Case Jr., harness racer
• Elisabeth Cavazza (1849–1926), author, journalist; born in Portland
• Joshua Chamberlain (1828–1914), Civil War Major General, Governor of Maine (1867–1871)
• Thomas Davee Chamberlain (1841–1896), Civil War Lieutenant Colonel, brother of Major General Joshua Chamberlain.
• Conrad Chase (born 1965), actor, singer; born in Portland
• Oren Burbank Cheney (1816–1903), student, teacher, principal Parsonsfield Seminary; Free Will Baptist clergyman; abolitionist; founding president of Bates College
• Yvon Chouinard (born 1938), founder of Black Diamond Equipment and Patagonia, born in Lewiston
• Cody Christian (born 1995), actor; Pretty Little Liars, Teen Wolf; born in Portland and grew up on a Penobscot reservation
• Frank Churchill (1901–1942), Oscar-winning composer for many Disney animated films; born in Rumford
• Carolyn Chute (born 1947), novelist, populist political activist; born in Portland; lives in Parsonsfield
• Nathan Clifford (1803–1881), Associate Justice of the United States Supreme Court, Attorney General of the United States; lived in Newfield
• Eunice Hale Cobb (1803–1880), writer, activist; born in Kennebunk
• William Cohen (born 1940), U.S. Congressman (1973–1979), Senator (1979–1997), US Secretary of Defense (1997–2001); born in and Mayor of Bangor (1971–1973)
• Samuel Colman (1832–1920), artist, writer, interior designer; born in Portland
• Susan Collins (born 1952), U.S. Senator from Maine; born in Caribou
• Ernie Coombs, Canadian Kid Show Host and Famous for Mr. Dressup
• Michelle Coombs, American geologist currently working in Alaska, but originally from Maine
• Jennie Maria Drinkwater Conklin (1841–1900), author, activist; born in Portland
• William Coperthwaite (1930–2013), educator and yurt advocate; born in Monticello
• Ron Corning (born 1971), TV host at WFAA in Dallas, Texas; raised in Calais
• Mike "Fluff" Cowan (born 1947), PGA Tour golf caddy; born in Winslow
• Ricky Craven (born 1966), ESPN broadcaster, NASCAR driver; born in Newburgh
• Laura Creavalle (born 1959), Guyanese-born Canadian/American professional bodybuilder; lives in Old Orchard Beach
• Ian Crocker (born 1982), three-time Olympic champion in swimming; born in Portland
• Effie Crockett (1856–1940), actress, wrote and composed the lullaby "Rock-a-bye Baby"; born in Rockland
• John Crowley (born 1942), author of fantasy, science fiction and mainstream fiction; born in Presque Isle
• Earl Cunningham (1893–1977), folk artist; born in Edgecomb
• Dick Curless (1932–1995), country singer; born in Fort Fairfield
• Ron Currie Jr. (born 1975), author; lives in Portland
• Robert Card, US Army Reserve Sergeant First Class (E-7) and mass murderer

D

• Sarah D'Alelio (born 1980), professional mixed martial artist; born in Belfast
• Robert L. Dale (1924–2020) pilot in Antarctica and namesake of the Dale Glacier; lived in Brunswick
• Frances Brackett Damon (1857–1939), poet, writer; born in Dexter
• Olive E. Dana (1859–1904), writer, poet; born in Augusta
• Bette Davis (1908–1989), two-time Oscar-winning actress; born in Massachusetts and lived in Cape Elizabeth
• Owen Davis (1874–1956), Pulitzer Prize-winning dramatist; born in Portland
• Howie Day (born 1981), singer; born and raised in Brewer
• William Deering (1826–1913), businessman and philanthropist, co-founder of International Harvester; born in South Paris
• Grace DeGennaro (born 1956), artist; resides in Yarmouth
• Patrick Dempsey (born 1966), actor; born in Lewiston
• Rick DiPietro (born 1981), NHL player; born in Lewiston
• Dorothea Dix (1802–1878), pioneering advocate for treatment and care of the handicapped and mentally ill; born in Hampden
• Nelson Dingley Jr. (1832–1899), Governor of Maine (1874–1876), US House of Representatives (1881–1899), responsible for the Dingley Tariff
• George Dole (1885–1928), Olympic gold medalist in freestyle wrestling at the 1908 Summer Olympics; born in Michigan and lived in Bath
• Jeff Donnell (1921–1988), actress; born in Windham
• Alice May Douglas (1865–1943), poet, author, editor; born in Bath
• Paul Douglas (1892–1976), economist and Illinois senator (1949–1967); partly raised in Onawa
• Cornelia M. Dow (1842–1905), philanthropist, temperance activist; born and died in Portland
• Brian Dumoulin (born 1991), NHL player, Pittsburgh Penguins; born in Biddeford
• Emma B. Dunham (1826–1910), poet, teacher; born in Minot; died in Deering

E

• Kevin Eastman (born 1962), comic book artist and writer; co-created Teenage Mutant Ninja Turtles; born in Springvale
• Stanley Boyd Eaton (born 1938), radiologist, one of the originators of the concept of Paleolithic nutrition; born in Old Town
• Gertrude Elliott (1874–1950), actress: stage, silent movies; born in Rockland
• Maxine Elliott (1868–1940), stage actress; born in Rockland
• Ellen Russell Emerson (1837–1907), author, ethnologist; born in New Sharon
• George Barrell Emerson (1797–1881), educator; born in Kennebunk

F

• Myrna Fahey (1933–1973), actress, Father of the Bride; born in Carmel
• Terry Farnsworth (born 1942), Canadian Olympic judoka
• Wallace Rider Farrington (1871–1933), journalist and government administrator, Territorial Governor of Hawaii (1921–1929); born in Orono
• Parker Fennelly (1891–1988), actor; born in Northeast Harbor
• William Pitt Fessenden (1806–1869), politician, Secretary of the Treasury (1864–1865); Congressman (1841–1843); Senator (1854–1864; 1865–1869); lived in Portland
• Greg Finley (born 1984), actor, The Secret Life of the American Teenager; born in Portland
• Frank Fixaris (1934–2006), sportscaster; resident of Falmouth
• Cooper Flagg (born 2006), basketball player; raised in Newport
• Ryan Flaherty (born 1986), professional baseball infielder and current coach; born in Portland
• James Flavin (1906–1976), film and television actor; born in Portland
• Charles Flint (1850–1934), businessman, founder of Computing-Tabulating-Recording Company which later became IBM; born in Thomaston
• Francis Ford (1881–1953), actor, writer, director, brother of John Ford; born in Portland
• John Ford (1894–1973), film director, winner of six Oscars; born in Cape Elizabeth, raised on Munjoy Hill in Portland
• Philip Ford (1900–1976), film director, nephew of John Ford; born in Portland
• Melville Fuller (1833–1910), eighth Chief Justice of the United States (1888–1910); born in Augusta
• Charlie Furbush (born 1986), baseball pitcher; born in Portland, attended St. Joseph's College of Maine

G

• Joey Gamache (born 1966), lightweight champion who boxed from 1976 to 2000; originally from Lewiston
• Peter A. Garland (1923–2005), politician, Congressman (1961–1963); lived in Brunswick
• Scott Garland (born 1973), WWE wrestler, ring name Scotty 2 Hotty; born in Westbrook
• Gladys George (1904–1954), actress, The Maltese Falcon, The Best Years of Our Lives; born in Patten
• Frank Bunker Gilbreth, Sr. (1868–1924), early advocate of scientific management and pioneer of motion study; born in Fairfield
• Jon Gillies (born 1994), ice hockey player; raised in South Portland
• Everett Glass (1891–1966), actor; born in Bangor
• Charles Goddard (1879–1951), playwright and screenwriter for silent films; born in Portland
• Jared Golden (born 1982), politician, Congressman (2019–); lives in Lewiston
• Gary Gordon (1960–1993), Master Sergeant in the U.S. Army who perished during Operation Gothic Serpent; born in Lincoln
• Chris Greeley (born 1962), was Cosmo magazine's Bachelor of the Month in June 1993. Appeared on multiple TV shows in the 1990s.
• Noah Gray-Cabey (born 1995), teen actor, My Wife and Kids, Heroes; raised in Newry
• Patty Griffin (born 1964), Grammy award-winning singer-songwriter and musician; born in Old Town
• Mace Greenleaf (1872–1912), stage and screen actor silent films
• Einar Gustafson (1935–2001), childhood cancer patient, namesake of The Jimmy Fund; born and raised in New Sweden

H

• Edwin Hall (1855–1938), physicist who discovered the "Hall effect"; born in Gorham
• John H. Hall (1781–1841), inventor of the M1819 Hall breech-loading rifle; mass production innovator; born in Portland
• Hannibal Hamlin (1809–1891), 15th Vice President of the United States and U.S. Senator; born in Paris
• Simon Hamlin (1866–1939), politician, Congressman (1935–1937); born in Standish
• Frank Handlen (1916–2023), artist and shipwright; born in Brooklyn, now the oldest resident in Kennebunkport
• Marsden Hartley (1877–1943), artist, poet; born in Lewiston
• George Haskins (1915–1991), law professor at the University of Pennsylvania Law School
• Juliana Hatfield (born 1967), guitarist and singer-songwriter; born in Wiscasset
• Garnet Hathaway (born 1991), NHL player; raised in Kennebunkport
• Heather Hemmens (born 1988), actress, Hellcats; raised in Waldo
• James Chico Hernandez (born 1954), Sambo martial artist; resides in Washburn
• Richard Herrick, received the first successful organ transplant from identical twin brother Ronald Herrick in 1954; born and lived in Maine
• Charlie Hewitt (born 1946), artist; born in Lewiston
• Joe Hill (born 1971), horror novelist; born in Hermon
• John Hodgman (born 1971), actor, writer and comedian; lives in Brooklin
• Will Holt (1929–2015), singer-songwriter, librettist and lyricist; born in Portland
• Winslow Homer (1836–1910), 19th-century painter; lived in Prouts Neck
• Oliver Otis Howard (1830–1909), United States Army officer and a Union general; born in Leeds
• Caroline Dana Howe (1824–1907), writer, poet, hymnwriter; born in Fryeburg
• Helen Marr Hurd (1839–1909), educator, poet; born in Harmony; died in St. Albans

I

• Robert Indiana (1928–2018), pop artist; lived in Vinalhaven

J

• Dave Jackson (1902–1978), Allagash Wilderness Waterway guide
• Sandi Jackson (born 1963), politician, former member of the Chicago City Council; born in Kittery
• Theodora R. Jenness (1847–1935), writer, editor; born in Greenwood
• Sarah Orne Jewett (1849–1909), novelist and short story writer; lived in South Berwick
• Jigger Johnson (1871–1935), logger and American folk hero known for his numerous off-the-job exploits

K

• Natalie Kalmus (1882–1965), "color supervisor" of virtually all Technicolor feature films made from 1934 to 1949; born in Houlton
• Linda Kasabian (born 1949), member of Charles Manson's "family"; born in Biddeford
• David E. Kelley (born 1956), Emmy-winning television producer and writer; born in Waterville
• Anna Kendrick (born 1985), Oscar-nominated actress, Jessica Stanley in The Twilight Saga; born in Portland
• Matthew Kenney (born 1964), celebrity chef, author, educator and entrepreneur; raised in Searsport; graduated from University of Maine at Orono
• Sumner Kimball (1834–1923), General Supt. of U.S. Life-Saving Service; born in Lebanon; raised in Sanford
• Angus King (born 1944), Governor of Maine (1995–2003), US Senator from Maine (since 2013); lives in Brunswick
• Owen King (born 1977), author; raised in Bangor
• Stephen King (born 1947), novelist whose books have sold more than 350 million copies; born in Portland; raised in Durham lives in Bangor.
• Tabitha King (born 1949), novelist, wife of Stephen King; born in Old Town lives in Bangor.
• William King (1788–1852), politician, first Governor of Maine (1820–1821); born in Scarborough

L

• Linda Lavin (born 1937), actress, Alice, six-time Tony Award nominee; born and raised in Portland
• Abby Fisher Leavitt (1836-1897), social reformer, newspaper publisher; born in Bangor
• Bud Leavitt Jr. (1917–1994), Bangor sportswriter, outdoor columnist, television host
• Paul LePage (born 1948), politician, Governor of Maine (2011–2019), Mayor of Waterville (2003–2011); born in Lewiston
• Roger Levesque (born 1981), former professional soccer player; born in Portland
• Enoch Lincoln (1788–1829), politician, Governor of Maine (1827–1829), US Congressman (1818–1826); lived in Augusta
• Tawny Little (born 1956), 1976 Miss America, television journalist; born in Portland
• Elle Logan (born 1987), 2008 Olympic gold medalist in women's rowing; born in Portland
• Alvin Orlando Lombard (1856–1937), inventor of continuous tracked vehicles; born in Springfield
• James B. Longley (1924–1980), first Independent Governor of Maine (1975–1979); born in Bangor
• James B. Longley Jr. (born 1951), politician, Congressman (1995–1997); born in Lewiston
• Barry B. Longyear (born 1942), novelist, author of Enemy Mine; lives in New Sharon
• Henry Wadsworth Longfellow (1807–1882), poet, born and raised in Portland; attended Bowdoin College
• Bob Ludwig (born 1945), audio mastering engineer, founder of Gateway Mastering and DVD in Portland

M

• Marc Macaulay (born 1957), actor, Burn Notice; born in Millinocket
• Frances Laughton Mace (1836–1899), poet; born in Orono
• Dick MacPherson (1930–2017), football coach; born in Old Town
• Nicole Maines (born 1997), actress, Supergirl, LGBT rights activist; lives in Portland
• Ella M. S. Marble (1850–1929), physician; born in Gorham; died in Paris
• Bob Marley (born 1967), stand-up comedian; from Portland; born in Bangor
• Andrea Martin (born 1947), actress, comedian, voice actress, SCTV, My Big Fat Greek Wedding, Kim Possible, Earthworm Jim; born in Portland
• H.S. Maxim (1840–1916), inventor of Maxim gun; born in Sangerville
• Julia Harris May (1833–1912), poet, teacher, founder; born in Strong
• David McCullough (1933–2022), author, historian, Pulitzer Prize winner; lived in Camden
• Cynthia McFadden (born 1956), co-anchor of Nightline and Primetime; born in Lewiston
• John McKernan (born 1948), politician, Governor of Maine (1987–1995), Congressman (1983–1987); born in Bangor
• Victor McKusick (1921–2008), physician, scientist, "father of medical genetics"; born in Parkman
• Vincent McKusick (1921–2014), attorney, Chief Justice of Maine Supreme Judicial Court; born in Parkman
• Christian McLaughlin (born 1967), TV writer, producer, novelist; born in Houlton
• Don McLean (born 1945), singer-songwriter; lives in Camden
• Vaughn Meader (1936–2004), comedian, impersonator, musician, film actor; born in Waterville
• Estelle M. H. Merrill (1858–1908), journalist, editor; born in Jefferson
• Helen Maud Merrill (1865–1943), litterateur, poet; born in Bangor; died in Portland
• Mike Michaud (born 1955), politician, Congressman (2003–2015); lives in East Millinocket
• Edna St. Vincent Millay (1892–1950); poet, born in Rockland
• Janet T. Mills (born 1948); politician, Governor of Maine (2019–); born in Farmington
• George J. Mitchell (born 1933), U.S. Senate Majority Leader, significant player in peace process of Northern Ireland; born in Waterville
• Herb Mitchell (1937–2011), actor, director; born in Bar Harbor
• Matthew Mulligan (born 1985), former NFL tight end; born in Bangor and lived in Enfield
• Edmund Muskie (1914–1996); politician, Governor and then Senator of Maine, and Democratic vice presidential nominee (1968), U.S. Secretary of State (1980–1981), born in Rumford

N

• Emma Huntington Nason (1845–1921), poet, author, musical composer; born in Hallowell
• John Neal (1793–1876), writer, critic, editor, lecturer, and activist; lived entire life in Portland except for sixteen years in Boston, Baltimore, and London^[2]
• Judd Nelson (born 1959), actor, The Breakfast Club, Suddenly Susan; born in Portland
• Louise Nevelson (1899–1988), sculptor of found objects; came to Maine when she was five and lived in Rockland
• Rachel Nichols (born 1980), actress, Alias, Star Trek, G.I. Joe: The Rise of Cobra; born and raised in Augusta
• Stephanie Niznik (1967–2019), actress, Everwood, Vanishing Son, Life Is Wild; born in Bangor
• Lillian Nordica (1857–1914), opera singer known as one of the foremost dramatic sopranos of the 19th and 20th centuries; born in Farmington
• William North (1755–1836), Revolutionary soldier, later made a General, aide-de-camp to Friedrich Wilhelm von Steuben, U.S. Senator from New York (1798); born in Pemaquid
• Edward Lawry Norton (1898–1983), Bell Labs engineer and scientist famous for developing the concept of the Norton equivalent circuit; born in Rockland

O

• Harry Oakes (1874–1943), discovered second-largest gold mine in Canada; mysteriously murdered in the Bahamas, which became basis of several books and movies; born in Sangerville
• Jeremiah O'Brien (1744–1818), naval officer of American Revolutionary War; born in Kittery
• John O'Hurley (born 1954), actor, voice actor, TV personality; J. Peterman on Seinfeld; born in Kittery

P

• Albion K. Parris (1788–1857), politician, Governor of Maine (1822–1827), US Senator (1827–1828); born in Hebron
• Gilbert Patten (1866–1945), author of the Frank Merriwell novels; born in Corinna
• Frannie Peabody (1903–2001), HIV/AIDS activist, helped establish The AIDS Project, and co-founded the Peabody House
• Waldo Peirce (1884–1970), artist, born in Bangor; lived most of his life in Maine
• Maynard Pennell (1910–1994), Boeing executive and chief engineer of the 707 prototype; born in Skowhegan
• Greenleaf Whittier Pickard (1877–1956), radio pioneer and 1926 IEEE Medal of Honor winner; born in Portland
• Chellie Pingree (born 1955), politician, Congresswoman (since 2009); lives in North Haven
• Bruce Poliquin (born 1953), politician, Congressman (2015–2019); born in Waterville, lives in Oakland
• John A. Poor (1808–1871), developer of the Portland gauge Maine railway system; born in Andover
• Quinton Porter (born 1982), NFL player; born in Portland
• Zach Porter (born 1989), singer-songwriter for Allstar Weekend; born in Bath
• Shirley Povich (1905–1998), sports columnist and reporter for The Washington Post; born in Bar Harbor

Q

• Althea G. Quimby (1858–1942), president, Woman's Christian Temperance Union of Maine; born in Norway

R

• Esther Ralston (1902–1994), silent film actress; born in Bar Harbor
• Thomas Brackett Reed (1839–1902), U.S. Representative from Maine, and Speaker of the U.S. House of Representatives, 1889–1891 and 1895–1899; born in Portland
• Lois Rice (1933–2017), businesswoman and educator, mother Susan Rice; born in Portland
• Derek Rivers (born 1994), NFL player; born in Augusta
• Edwin Arlington Robinson (1869–1935), poet; born in Alna and raised in Gardiner
• Aaron Robinson (born 1970), composer; born in Camden and raised in Waldoboro.
• Duncan Robinson (born 1994), professional basketball player; born in York
• Nelson Rockefeller (1908–1979), businessman, philanthropist, public servant, Vice President of the United States (1974–1977) and Governor of New York (1959–1973); born in Bar Harbor
• Charles Rocket (1949–2005), actor, Saturday Night Live, Tequila and Bonetti, Dumb and Dumber; born in Bangor
• Lou Rogers (1879–1952), suffrage cartoonist, writer, and radio personality, born in Patten
• Daniel Rose (1772–1835), politician, Governor of Maine (1822); lived in Thomaston
• Henrietta Gould Rowe (1834/35-1910), litterateur, author; born in East Corinth
• Victoria Rowell (born 1959), actress, The Young and the Restless, Diagnosis: Murder, Dumb and Dumber; born and raised in Portland
• Travis Roy (1975–2020), college ice hockey player; born in Augusta
• Robert Rushworth (1924–1993), U.S. Air Force major general and test pilot; born in Madison

S

• Tim Sample (born 1951), humorist and author; born in Fort Fairfield and raised in Boothbay Harbor
• Sue A. Sanders (1842–1931), teacher, clubwoman, author; born in Casco
• Louis Sockalexis (1871–1931), professional baseball player; born in Penobscot Indian Island Reservation
• Salome Sellers (1800–1909), centenarian, born in Deer Isle, Maine
• Tony Shalhoub (born 1953), actor; attended University of Southern Maine
• Reta Shaw (1912–1982), actress, The Ghost & Mrs. Muir, Mary Poppins; born in South Paris
• Arthur Shawcross (1945–2008), serial killer; born in Kittery
• Timothy Simons (born 1978), actor, Veep; born in Readfield
• Mark Sisson (born 1953), blogger and co-founder of Primal Kitchen
• Albion Woodbury Small (1854–1926), sociologist and founder of first university department of sociology in United States; born in Buckfield and raised in Bangor
• Taylor Small (born 1994), politician, member of the Vermont House of Representatives (2021–present); born in Portland
• Margaret Chase Smith (1897–1995), first woman to serve in both houses of U.S. Congress (1940–1973);^[3] first woman to have her name placed in nomination for the Presidency at a major political party's convention;^[4] born in Skowhegan^[5]
• Samantha Smith (1972–1985), child peace activist, child actress; born in Houlton, later lived in Manchester
• Olympia Snowe (born 1947), Congresswoman and U.S. Senator; born in Augusta and raised in Auburn
• Kate Snow (born 1969), television journalist for NBC News; born in Bangor
• Brett Somers (1922–2007), actress; born in Canada and raised in Portland
• Susan Marr Spalding (1841–1908), poet; born in Bath
• Aly Spaltro (born 1989), musician known professionally as Lady Lamb; began her recording career in Brunswick
• Ellis Spear (1834–1917), Civil War Lieutenant Colonel of the 20th Maine Infantry Regiment
• Percy Spencer (1894–1970), inventor of the microwave oven; born in Howland
• Spose (born 1985), rapper, podcaster; lives in Wells
• Andrew St. John (born 1982), actor, General Hospital, Life Is Wild; born in Millinocket
• Bob Stanley (born 1954), former professional baseball player, pitched for Boston Red Sox in 1986 World Series; born in Portland
• Cordelia Stanwood (1865–1968), teacher, ornithologist, and wildlife photographer
• C. A. Stephens (1844–1931), writer and gerontologist; born and died in Norway, Maine
• C. J. Stevens (1927–2021), author; born in Smithfield and has lived in Phillips, Weld, and Temple
• Harriet Beecher Stowe (1811–1896), author of Uncle Tom's Cabin; lived in Brunswick
• Noel Paul Stookey (born 1937); folk singer and songwriter; member of Peter Paul and Mary group; resides in Blue Hill
• Charlie Summers (born 1956); politician, Secretary of State of Maine (2011–2013); lives in Biddeford
• Mandy Sumner (born 1978) World Record Holder for the longest bi-fin swim under ice by a woman in a swimsuit in 2024; from North Berwick
• Bill Swift (born 1961), former professional baseball pitcher; born in Portland
• Tim Sylvia (born 1976), mixed martial arts fighter, professional wrestler; born in Ellsworth

T

• Drew Taggart (born 1989), musician, DJ, singer of the Chainsmokers; grew up in Freeport
• Gerald Talbot (born 1931), Maine state legislator (1972–1978), African American civil rights activist; born in Bangor
• Phyllis Thaxter (1919–2012), actress, born in Portland
• Augustin Thompson (1835–1903), creator of Moxie, born in Union
• Brigadier Samuel Thompson (1734–1798), soldier of the American Revolutionary War; lived in Brunswick
• Gary Thorne (born 1948), sportscaster, born in Bangor
• Andrew J. Tozier (1838–1910), soldier, Congressional Medal of Honor recipient; born in Litchfield
• Novella Jewell Trott (1846–1929), author, editor; born in Woolwich
• Jeff Turner (born 1962), retired professional basketball player; born in Bangor
• Liv Tyler (born 1977), actress, daughter of Aerosmith singer Steven Tyler; grew up in Maine

U

• John G. Utterback (1872–1955), politician, Congressman (1933–1935); lived in Bangor

V

• Donald Valle (1908–1977), founder and owner of Valle's Steak House restaurant chain; born in Italy, moved to Portland in 1912
• Richard Valle (1931–1995), son of Donald Valle and owner of eponymously named Valle's Steak House; born in Portland
• Rudy Vallée (1901–1986), singer, actor, bandleader, and entertainer; lived in Westbrook
• Todd Verow (born 1966), filmmaker, cinematographer, actor; born in Bangor

W

• Oliver Wahlstrom (born 2000), hockey player; born in Yarmouth
• John Bruce Wallace (born 1950), composer, musician, author; born in Calais
• Dan Walters (1966–2020), baseball player; born in Brunswick
• Sam Webb (born 1945), former chairman of Communist Party USA; born in Maine
• Janwillem van de Wetering (1931–2008), novelist; lived in Blue Hill
• Clarence White (1944–1973), bluegrass, country rock, and rock guitarist; born in Lewiston
• E. B. White (1899–1985), essayist, author, humorist, poet; lived in Brooklin
• Ellen G. White (1827–1915), author, co-founder of the Seventh-day Adventist Church; born in Gorham
• Charles Whitman (1842–1910), zoologist, influential to the founding of classical ethology; born in Woodstock
• JoAnn Willette (born 1963), actress, Just the Ten of Us; born in Lewiston
• William D. Williamson (1779–1846) politician, Governor of Maine (1821); lived in Bangor
• Dorothy Clarke Wilson (1904–2003), author, playwright; born in Gardiner
• Abba Goold Woolson (1838–1921), writer; born in Windham
• Andrew Wyeth (1917–2009), 20th-century painter; had a home in Cushing
• Jamie Wyeth (born 1946), contemporary painter; has lived in Maine since the mid-1960s
• N. C. Wyeth (1882–1945), artist and illustrator; bought a home in Port Clyde in the 1930s
• Nick Wyman (born 1950), actor, Die Hard with a Vengeance; born in Portland

Z

• Steven Zirnkilton (born 1958), voice actor and former politician; lives in Seal Harbor