In public transport, Route 2 may refer to:
- Barcelona Metro line 2
- NWFB Route 2 in Hong Kong
- London Buses route 2
- Line 2 (Madrid Metro)
- Line 2 Orange (Montreal Metro)
- 2 (New York City Subway service)
- Seoul Subway Line 2
- Shanghai Metro Line 2
This article includes a list of related items that share the same name (or similar names).