This is a list of regions of Uruguay by Human Development Index as of 2023 with data for the year 2021.^[1]

Rank	Region	HDI (2021)
Very high human development
1	Montevideo	0.826
2	Costa Este (Canelones, Maldonado and Rocha)	0.812
–	Uruguay	0.809
3	Centro Sur (Flores, Florida and Lavalleja)	0.807
High human development
4	Centro (Durazno and Tacuarembó)	0.784
6	Norte (Artigas, Rivera, Cerro Largo and Treinta y Tres)	0.777
5	Litoral Sur (Soriano, Colonia and San José)	0.784
7	Litoral Norte (Paysandú, Salto and Río Negro)	0.769