This is a list of rivers in Guyana.

By drainage basin

This list is arranged by drainage basin, with respective tributaries indented under each larger stream's name.

Atlantic Ocean

• Amazon River (Brazil)
  • Negro River (Brazil)
    • Branco River (Brazil)
      • Takutu River
        • Ireng River
• Courantyne River^[1]
  • Kutari River
  • Coeroeni River
  • New River (South America)
    • Oronoque River
• Berbice River
  • Canje River
• Abary River
• Mahaicony River
• Mahaica River
• Demerara River^[1]
  • Haiama River
  • Haianari Creek
  • Haiakwa Creek
  • John River
  • Madawini
  • Kamuni
  • Hauraruni
  • Tenabu
  • Madabadeen

• Essequibo River
  • Mazaruni River^[1]
    • Kako River
    • Kukui
    • Kamarang River
      • Eping River
    • Issineru River
    • Meamu River
    • Kurupung River
    • Merume River
    • Puruni River
  • Cuyuni River^[1]
    • Akarabisi
    • Arimu River
    • Ekereku River
    • Iroma
    • Akarabisi
    • Kopang
    • Oko River
    • Wenamu River
      • Akaiwang River
  • Potaro River
    • Arnik River
    • Kuribrong River
  • Konawaruk River
  • Siparuni River
    • Burro-Burro River
  • Rupununi River
    • Rewa River
      • Kwitaro River
  • Kuyuwini River
  • Kassikaityu River
• Pomeroon River
  • Wakapau River
• Moruka River
• Waini River
  • Barama River
• Orinoco River (Venezuela)
  • Barima River
    • Kaituma River
  • Amacuro River (Amakura River)