| Tenure | Incumbent | Notes |
|---|---|---|
| ante 1730 | Foundation of Akuapem state | |
| Akuapemhene (Rulers) | ||
| Asona dynasty | ||
| ???? to ???? | Safori, Akuapemhene (Nana Ofori Dua) |
|
| ???? to ???? | Nana Okyerema Manukure, Akuapemhene | |
| ???? to ???? | Nana Ofei Boa, Akuapemhene | |
| ???? to ???? | Nana Ofei Amanapa, Akuapemhene | |
| ???? to ???? | Nana Ofei Ntoakyerewa, Akuapemhene | |
| ???? to 1730 | Nana Amaniafim, Akuapemhene | |
| 1730 to 1731 | Nana Ofori Kuma I, Akuapemhene (Sakyiama Tenten) (Kwao Safori) |
|
| 1731 to 1742 | Nana Fianko Betuafo, Akuapemhene | |
| 1742 to 1765 | Nana Kwapon Kyerefo, Akuapemhene | |
| 1765 to 1792 | Nana Obuobi Atiemo, Akuapemhene | |
| 1792 to 1802 | Nana Awuku Fenenee, Akuapemhene | |
| September 1802 to December 1802 | Nana Ohene Kuma, Akuapemhene | |
| December 1802 to 1816 | Nana Kwao Saforo Twie, Akuapemhene | |
| 1816 to 1836 | Nana Addo Dankwa I, Akuapemhene | |
| 1837 to 1 November 1845 | Nana Adum Tokori, Akuapemhene | |
| 1846 to 1866 | Nana Kwadade I, Akuapemhene | |
| 1866 to 1876 | Nana Asa Krefa, Akuapemhene | |
| 1876 to 1879 | Nana Kwame Tawia, Akuapemhene | |
| 1880 to 1895 | Nana Kwame Fori I, Akuapemhene | |
| 1895 to 1907 | Nana Kwasi Akuffo, Akuapemhene | 1st Term |
| 1907 to 8 May 1914 | Nana Charles Owusu Ansa, Akuapemhene | |
| 23 May 1914 to May 1919 | Nana Ofori Kuma II, Akuapemhene | 1st Term |
| May 1919 to 1920 | Interregnum | |
| 1920 to 1927 | Nana Kwasi Akuffo, Akuapemhene | 2nd Term |
| 1927 to 1930 | Addo Dankwa II, Akuapemhene | |
| 1930 to 1932 | Interregnum | |
| 1932 to 1941 | Nana Ofori Kuma II, Akuapemhene | 2nd Term |
| 1941 to 1944 | Interregnum | |
| 1944 to 1945 | Nana Kwadade II, Akuapemhene | |
| 1945 to 1949 | Nana Kwame Fori II, Akuapemhene | 1st Term |
| 1949 to 1959 | Nana Twumhene, Akuapemhene | |
| 1959 to post/c. 1972 | Nana Kwame Fori II, Akuapemhene | 2nd Term |
| 1974 to 2015 | Nana Addo Dankwa III, Akuapemhene | |
| 2015 to 2020 | Interregnum | |
| 2020 to present | Oseadeeyo Kwasi Akuffo III, Akuapemhene | |
| 1994 | Akuapem Okere, Akuapem Anafo, Akuapem Guan states created through secession | |