The following science-fiction TV shows and radio programs have been produced exclusively or mostly in Canada. (Science-fiction related genres include Fantasy, Horror, and Supernatural.) Many of these programs have been run and/or produced by American or other international production companies. (See Canadian science fiction for more information.) Series in bold have the in-universe story take place in Canada or have Canadian characters in them.

Live action science fiction television drama series

1950s debut

• Space Command (1953)
• The Man from Tomorrow (1958)

1970s debut

• The Hilarious House of Frightenstein (1971)
• The Starlost (1973)
• Peep Show (1975)
• Read All About It! (1979)

1980s debut

• The Hitchhiker (1983)
• Friday the 13th: The Series (1985)
• The New Alfred Hitchcock Presents (1985)
• The Ray Bradbury Theater (1985)
• Airwolf (1987)
• Captain Power (1987)
• Earth Star Voyager (1988)
• My Secret Identity (1988)
• War of the Worlds (1988)

1990s debut

• Counterstrike (1990)
• Maniac Mansion (1990)
• Beyond Reality (1991)
• The Hidden Room (1991)
• Forever Knight (1992)
• Highlander: The Series (1992)
• Nightmare Cafe (1992)
• The Odyssey (1992)
• Matrix (1993)
• The X-Files (1993) first five seasons filmed in Vancouver, later seasons in Los Angeles
• M.A.N.T.I.S. (1994)
• Robocop: The Series (1994)
• TekWar (1994)
• Viper (1994)
• Deepwater Black (1995)
• Mysterious Island (1995)
• The Outer Limits (1995)
• Sliders (1995) first two seasons filmed in Vancouver, later seasons in Los Angeles
• Strange Luck (1995)
• VR.5 (1995)
• Poltergeist: The Legacy (1996)
• The Pretender (1996)
• Profit (1996)
• Psi Factor: Chronicles of the Paranormal (1996)
• The Sentinel (1996)
• Space Cases (1996)
• Cloned (1997)
• Doomsday Rock (1997)
• Earth: Final Conflict (1997)
• Honey, I Shrunk the Kids: The TV Show (1997)
• Lexx (1997)
• Night Man (1997)
• Ninja Turtles: The Next Mutation (1997)
• Sleepwalkers (1997)
• Stargate SG-1 (1997)
• Animorphs (1998)
• Eerie, Indiana: The Other Dimension (1998)
• First Wave (1998)
• Highlander: The Raven (1998)
• Mercy Point (1998)
• Seven Days (1998) 1st season in California, later season in Vancouver
• Welcome to Paradox (1998)
• BeastMaster (1999)
• Big Wolf on Campus (1999)
• Code Name: Eternity (1999)
• Harsh Realm (1999)
• Relic Hunter (1999)
• Strange World (1999)
• Sir Arthur Conan Doyle's The Lost World (1999)
• So Weird (1999)
• Total Recall 2070 (1999)

2000s debut

• Andromeda (2000)
• Dark Angel (2000)
• Freedom (2000)
• The Immortal (2000)
• Level 9 (2000)
• Mysterious Ways (2000)
• The Others (2000) Pilot filmed in Vancouver, the rest of the season's in California.
• The Secret Adventures of Jules Verne (2000)
• Sole Survivor (2000)
• The Zack Files (2000)
• The Chronicle (2001)
• The Lone Gunmen (2001)
• Mutant X (2001)
• MythQuest (2001)
• Night Visions (2001)
• Smallville (2001)
• Special Unit 2 (2001)
• Starhunter (2001)
• Tracker (2001)
• Vampire High (2001)
• Wolf Lake (2001)
• 2030 CE (2002)
• The Dead Zone (2002) For the sixth season, production moved to Montreal.
• Galidor: Defenders of the Outer Dimension (2002)
• Haunted (2002)
• Jeremiah (2002)
• John Doe (2002)
• Odyssey 5 (2002)
• Strange Days at Blake Holsey High (2002)
• Taken (2002)
• Alienated (2003)
• Jake 2.0 (2003)
• Miracles (2003)
• The Twilight Zone (2003)
• The 4400 (2004)
• Battlestar Galactica (2004)
• The Collector (2004)
• Kingdom Hospital (2004)
• ReGenesis (2004)
• Stargate Atlantis (2004)
• Charlie Jade (2005)
• Tru Calling (2005)
• Blade: The Series (2006)
• EUReKA (2006)
• Kyle XY (2006)
• Masters of Science Fiction (2006)
• Three Moons Over Milford (2006)
• A.M.P.E.D (2007)
• Bionic Woman (2007)
• Blood Ties (2007)
• Dinosapien (2007)
• Flash Gordon (2007)
• Grand Star (2007)
• Painkiller Jane (2007)
• Reaper (2007)
• Unnatural History (2007)
• The Andromeda Strain (2008)
• Caprica (2008)
• Fear Itself (2008)
• Fringe (2008) Pilot filmed in Toronto, 1st season in New York City, later seasons in Vancouver
• Sanctuary (2008)
• Aaron Stone (2009)
• Being Erica (2009)
• Defying Gravity (2009)
• Harper's Island (2009)
• The Listener (2009)
• Stargate Universe (2009)
• Storm World (2009)
• The Troop (2009)
• Warehouse 13 (2009)

2010s debut

• Haven (2010)
• Les Rescapés (2010)
• Lost Girl (2010)
• R.L. Stine's The Haunting Hour (2010)
• Tower Prep (2010)
• Alcatraz (2012)
• Arrow (2012)
• Continuum (2012)
• Primeval New World (2012)
• Defiance (2013)
• Orphan Black (2013)
• The Tomorrow People (2013)
• The 100 (2014)
• Ascension (2014)
• The Flash (2014)
• Helix (2014)
• 12 Monkeys (2015)
• Between (2015)
• Dark Matter (2015)
• The Expanse (2015)
• Killjoys (2015)
• Minority Report (2015)
• Olympus (2015)
• Travelers (2016)
• Van Helsing (2016)
• Wynonna Earp (2016)

2020s debut

• Utopia Falls (2020)

Documentaries/Newsmagazine shows

• The Nature of Things (1960)
• Science Magazine (1975)
• Science International (1976)
• Prisoners of Gravity (1989)
• The Anti Gravity Room (1996)
• 2001: A Space Road Odyssey (2001)
• HypaSpace (2002)
• Proof Positive (2004)
• Beyond, The Series (2005)
• Shadow Hunter (2005)

French-language shows

• Lunatiques (1999)
• Dans une galaxie près de chez vous (1998)

Animation

• The Marvel Superheroes (1966)
• Rocket Robin Hood (1966)
• Spider-Man (1967)
• Inspector Gadget (1983)
• ReBoot (1993)
• Tales From the Cryptkeeper (1993)
• Beast Wars (1996)
• Robocop: Alpha Commando (1998)
• Shadow Raiders (1998)
• Beast Machines (1999)
• Action Man (2000)
• Heavy Gear (2001)
• Xcalibur (2001)
• Spider-Man: The New Animated Series (2003)
• Atomic Betty (2004)
• Dark Oracle (2004)
• Delta State (2004)
• Dragon Booster (2004)
• Tripping the Rift (2004)
• Zeroman (2004)
• Zixx (2004)
• Get Ed (2005)
• Station X (2005)
• Di-Gata Defenders (2006)
• Spider Riders (2006)
• Storm Hawks (2007)
• Bakugan Battle Brawlers (2008)
• Escape from Planet Earth (2009)
• Max Steel (2013)
• Bakugan: Battle Planet (2018)

Radio

• Nazi Eyes on Canada (1942) CBC radio series
• Johnny Chase: Secret Agent of Space (1978) CBC radio series
• Nightfall (1980) CBC radio series
• Vanishing Point (1984) CBC radio series
• Soundings (1985) radio drama produced by Jeff Green, originally aired on CHEZ 106 and later CBC
• Faster Than Light (2002) CBC radio pilot (broadcast Sept 22nd, 2002 on Sunday Showcase (in mono) and again Sept 23rd on Monday Night Playhouse (in stereo).
• Canadia: 2056 (2007) CBC radio series

Telefilms

• The Incredible Hulk Returns (1988)
• Bionic Showdown: The Six Million Dollar Man and the Bionic Woman (1989)
• The Trial of the Incredible Hulk (1989)
• The Death of the Incredible Hulk (1990)
• It (1990)
• TekWar: TekJustice (1994)
• TekWar: TekLab (1994)
• TekWar: TekLords (1994)
• Tekwar: The Movie (1994)
• Generation X (1996)
• Trilogy of Terror II (1996)
• Nick Fury: Agent of S.H.I.E.L.D. (1998)
• Atomic Train (1999)
• Ginger Snaps (2000)
• RoboCop: Prime Directives (2000)
• The Pretender 2001 (2001)
• The Pretender: Island of the Haunted (2001)
• Babylon 5: The Legend of the Rangers (2002)
• Carrie (2002)
• Kaput and Zösky: The Ultimate Obliterators (2002)
• Saint Sinner (2002)
• A Wrinkle in Time (2003)
• Hot Wheels Highway 35 World Race (2003)
• 5ive Days to Midnight (2004)
• Decoys (2004)
• Earthsea (2004)
• Ginger Snaps: Unleashed (2004)
• Ginger Snaps Back: The Beginning (2004)
• Meltdown (2004) (2004)
• Snakehead Terror (2004)
• Acceleracers: Speed of Silence (2005)
• Deadly Skies (2005)
• The Last Templar (2005)
• Painkiller Jane (2005)
• Rapid Fire (2005)
• AcceleRacers: Breaking Point (2006)
• AcceleRacers: The Ultimate Race (2006)
• Earthstorm (2006)
• Savage Planet (2006)
• Fire Serpent (2007)
• KAW (2007)
• Tin Man (2007)
• Swamp Devil (2008)
• The Phantom (2009)
• Virtuality (2009)
• Paradox (2010)

Web series

• Sanctuary (2007)