This is a list of people who have served as Lord Lieutenant of Roxburgh, Ettrick and Lauderdale. This office replaced the Lord Lieutenant of Roxburghshire and the Lord Lieutenant of Selkirkshire in 1975.

• Buccleuch had been Lord Lieutenant of Roxburghshire and Selkirkshire
• John Scott, 9th Duke of Buccleuch, 1975–1998
• June Paterson-Brown, 7 December 1998 – 2007
• Gerald Maitland-Carew, 28 March 2007 – 28 December 2016^[1]
• Richard Scott, 10th Duke of Buccleuch, 28 December 2016 – present^[2]