Mary Cooper may refer to:

• Mary Cooper (publisher) (died 1761), English publisher and bookseller
• Mary Little Cooper (born 1946), U.S. federal judge
• Mary-Charlotte Cooper, bassist and vocalist for The Subways

Characters

• Mary Cooper (The Big Bang Theory), a character in The Big Bang Theory
• Mary Cooper (Torchwood), a recurring character in Torchwood
• Mary Cooper, a character in Harlots