Mast cell sarcoma
SpecialtyOncology
Usual onsetCan occur at any age.[1]
PrognosisThe median survival time is less than 18 months

Mast cell sarcoma is an extremely aggressive[2] form of sarcoma made up of neoplastic mast cells. A sarcoma is a tumor made of cells from connective tissue. Mast cell sarcoma is an extremely rare tumor. Only three cases have been are reported so far[when?]. Prognosis is extremely poor. People with a mast cell sarcoma have no skin lesions, and pathology examination of the tumor shows it to be very malignant with an aggressive growth pattern.[3] Mast cell sarcoma should not be confused with extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases observed, mast cell sarcoma terminated quickly as mast cell leukemia; one of the most aggressive human cancers.[4]

See also

References

  1. ^ Monnier J., Georgin-Lavialle S., Canioni D., Lhermitte L., Soussan M., Arock M., Bruneau J., Dubreuil P., Bodemer C., Chandesris M., Lortholary O., Hermine O., Damaj G. et al Mast cell sarcoma: new cases and literature review. Oncotarget. 2016; 7: 66299-66309. Retrieved from https://www.oncotarget.com/article/11812/text/
  2. ^ Chott A, Guenther P, Huebner A, Selzer E, Parwaresch R, Horny H, Valent P (2003). "Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma". Am J Surg Pathol. 27 (7): 1013–9. doi:10.1097/00000478-200307000-00019. PMID 12826896. S2CID 46710032.
  3. ^ Nancy Gould, "Diagnosis and Classification of Mastocytosis Archived 2004-10-27 at the Wayback Machine", The Mastocytosis Society.
  4. ^ Ansell SM, ed. (2008). Rare Hematological Malignancies. Cancer Treatment & Research. Springer.

External links


Classification
Myeloid-related haematological malignancy
Connective/soft tissue tumors and sarcomas
Categories