Microsoft Mesh is a cloud-based platform for collaboration in mixed reality, offering it both as an app and as a service. Microsoft Mesh leverages Microsoft 365 to allow people in different physical locations, using different types of devices, to participate and collaborate in a shared immersive space. There are two different applications of Mesh: Immersive Spaces in Teams and custom environments that are developed with Unity and currently used with a dedicated Mesh client application.

While Microsoft makes the Hololens 2 and has partnered with most major PC manufacturers like HP to build Windows Mixed Reality VR headsets, Microsoft Mesh is designed to be device and operating system agnostic, however, it currently supports only Windows and Meta VR headsets.

It makes use of elements of the AltspaceVR platform Microsoft acquired in 2017.^[1]