The Midwest Football Conference was a football conference for National Junior College Athletic Association (NJCAA) teams located in the [[Midwestern United States ]]. It was formed when the North Central Community College Conference merged with the Iowa Conference in 2005.
The conference dissolved following the 2013 season after almost all of the East Division schools, except the College of DuPage, dropped football. The Iowa schools, Ellsworth Community College, Iowa Central Community College and Iowa Western Community College, formed a scheduling alliance with the Kansas Jayhawk Community College Conference. The two North Dakota schools joined the Minnesota Community College Conference in football only while DuPage became an independent.
Grand Rapids, Harper, Joliet, Rock Valley and North Iowa Area no longer field teams.
East division
| School | Team Name | Location |
| College of DuPage | Chaparrals | Glen Ellyn, Illinois |
| Grand Rapids Community College | Raiders | Grand Rapids, Michigan |
| Harper College | Hawks | Palatine, Illinois |
| Joliet Junior College | Wolves | Joliet, Illinois |
| Rock Valley College | Golden Eagles | Rockford, Illinois |
West division
| School | Team Name | Location |
| Ellsworth Community College | Panthers | Iowa Falls, Iowa |
| Iowa Central Community College | Tritons | Fort Dodge, Iowa |
| Iowa Western Community College | Reivers | Council Bluffs, Iowa |
| North Dakota State College of Science | Wildcats | Wahpeton, North Dakota |
| North Iowa Area Community College | Trojans | Mason City, Iowa |
