| mir-370 | |
|---|---|
| Identifiers | |
| Symbol | mir-370 |
| Rfam | RF00740 |
| miRBase family | MIPF0000167 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-370 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. This microRNA, mir-370-3p, has been shown to play a role in heart failure. The upregulation of mir-370-3p in the sinus node leads to downregulation of the pacemaker ion channel, HCN4, and thus downregulation of the corresponding ionic current, which causes sinus bradycardia.[1]
miRNA precursor families | |
|---|---|
| 1-100 | |
| 101-200 | |
| 201-300 | |
| 301-400 | |
| 401+ | |
| Other | |