mir-395 microRNA precursor family
Predicted secondary structure and sequence conservation of mir-395
Identifiers
Symbolmir-395
RfamRF00451
miRBaseMI0001007
miRBase familyMIPF0000016
Other data
RNA typeGene; miRNA
Domain(s)Eukaryota
GOGO:0035195 GO:0035068
SOSO:0001244
PDB structuresPDBe

mir-395 is a non-coding RNA called a microRNA that was identified in both Arabidopsis thaliana and Oryza sativa computationally and was later experimentally verified. mir-395 is thought to target mRNAs coding for ATP sulphurylases.[1] The mature sequence is excised from the 3' arm of the hairpin.

miR-395 is upregulated in Arabidopsis during sulphate-limited conditions, when the mature miRNA then regulates sulphur transporters and ATP sulphurylases.[2][3]

References

  1. ^ Jones-Rhoades MW, Bartel DP (June 2004). "Computational identification of plant microRNAs and their targets, including a stress-induced miRNA". Molecular Cell. 14 (6): 787–99. doi:10.1016/j.molcel.2004.05.027. PMID 15200956.
  2. ^ Liang G, Yang F, Yu D (June 2010). "MicroRNA395 mediates regulation of sulfate accumulation and allocation in Arabidopsis thaliana". The Plant Journal. 62 (6): 1046–57. doi:10.1111/j.1365-313X.2010.04216.x. PMID 20374528.
  3. ^ Liang G, Yu D (October 2010). "Reciprocal regulation among miR395, APS and SULTR2;1 in Arabidopsis thaliana". Plant Signaling & Behavior. 5 (10): 1257–9. doi:10.4161/psb.5.10.12608. PMC 3115361. PMID 20935495.

External links


miRNA precursor families
Categories