Monocytopenia
SpecialtyHematology

Monocytopenia is a form of leukopenia associated with a deficiency of monocytes.

It has been proposed as a measure during chemotherapy to predict neutropenia,[1] though some research indicates that it is less effective than lymphopenia.[2]

Causes

The causes of monocytopenia include: acute infections, stress, treatment with glucocorticoids, aplastic anemia, hairy cell leukemia, acute myeloid leukemia, treatment with myelotoxic drugs, intestinal resection, and genetic syndromes, as for example MonoMAC syndrome.[3]

Diagnosis

- Blood Test (CBC) (Normal range of Monocytes: 1-10%) (Normal range in males: 0.2-0.8 x 10 3 /microliter)[citation needed]

- Blood test checking for monocytopenia (Abnormal ranges: <1%) (Abnormal range in males: <0.2 x 10 3 /microliter)[citation needed]

Treatment

Monocytopenia may be treated with hematopoietic stem cell transplantation. [4]

References

  1. ^ Kondo M, Oshita F, Kato Y, Yamada K, Nomura I, Noda K (1999). "Early monocytopenia after chemotherapy as a risk factor for neutropenia". Am. J. Clin. Oncol. 22 (1): 103–5. doi:10.1097/00000421-199902000-00025. PMID 10025393.
  2. ^ Oguz A, Karadeniz C, Ckitak EC, Cil V (2006). "Which one is a risk factor for chemotherapy-induced febrile neutropenia in childhood solid tumors: early lymphopenia or monocytopenia?". Pediatr Hematol Oncol. 23 (2): 143–51. doi:10.1080/08880010500457673. PMID 16651243. S2CID 35305292.
  3. ^ Harrison's principles of internal medicine. New York: McGraw-Hill. 2005. pp. 356. ISBN 978-0-07-140235-4.
  4. ^ "Monocytopenia - Hematology and Oncology". Merck Manuals Professional Edition. Retrieved 2023-08-23.

External links

Classification
Diseases of monocytes and granulocytes
Category