Ethanolamine Oleate
Clinical data
AHFS/Drugs.comMultum Consumer Information
ATC code
Identifiers
  • 2-Hydroxyethylammonium oleate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.017.163 Edit this at Wikidata
Chemical and physical data
FormulaC20H41NO3
Molar mass343.552 g·mol−1
Density0.974 g/cm3
 ☒NcheckY (what is this?)  (verify)

Monoethanolamine oleate (ethanolammonium oleate) is an organic compound with the formula [CH3(CH2)7CH=CH(CH2)7CO2][H3NCH2CH2OH].. A colorless oily liquid, it is an example of a protic ionic liquid.[1] It is a salt formed by the reaction between monoethanolamine and oleic acid.[2]

Antivaricose agent

As an antivaricose agent, it is injected topically into varicosities to cause sclerosis (closure) of the abnormal vein. It is indicated for the treatment of patients with esophageal varices that have recently bled, to prevent rebleeding. Ethanolamine is not indicated for the treatment of patients with esophageal varices that have not bled. There is no evidence that treatment of this population decreases the likelihood of bleeding. Sclerotherapy with ethanolamine has no beneficial effect upon portal hypertension, the cause of esophageal varices, so that recanalization and collateralization may occur, necessitating reinjection.[3]

References

  1. ^ Toledo Hijo AA, Maximo GJ, Costa MC, Cunha RL, Pereira JF, Kurnia KA, et al. (April 2017). "Phase Behavior and Physical Properties of New Biobased Ionic Liquid Crystals". The Journal of Physical Chemistry B. 121 (14): 3177–3189. doi:10.1021/acs.jpcb.7b01384. PMID 28332847.
  2. ^ Álvarez VH, Mattedi S, Martin-Pastor M, Aznar M, Iglesias M (2010). "Synthesis and Thermophysical Properties of Two New Protic Long-Chain Ionic Liquids with the Oleate Anion". Fluid Phase Equilibria. 299: 42–50. doi:10.1016/j.fluid.2010.08.022.
  3. ^ "Ethanolamine Oleate". RXList. Retrieved 7 March 2020.


Categories