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Moser Channel is the deepest passage spanned by the Seven Mile Bridge and is one of four predominant passages in the Florida Keys which allow exchange of waters to the north and west of the Keys (including Florida Bay and the Gulf of Mexico) with the Atlantic waters of Hawk Channel and the Florida Reef to the south and east. Moser Channel has an orientation perpendicular to the bridge. The other three Keys passages important to the exchange of south Florida coastal waters are Long Key Channel, Channel 5, and Channel 2.

24°42′00″N 81°10′11″W / 24.70000°N 81.16972°W / 24.70000; -81.16972

v t e Florida Keys
Biscayne National Park	Soldier Ragged Boca Chita Sands Elliott Adams Caesar's Rock Meig's Rubicon Reid Porgy Totten Old Rhodes Islandia
Upper keys	Key Largo Island CDP North Tavernier Plantation Island former CDP Windley Upper Matecumbe Tea Table Indian Lignumvitae Lower Matecumbe Islamorada
Middle keys	Craig Fiesta Long Layton Conch Little Duck Key Island CDP Grassy Crawl Little Long Point Fat Deer Vaca Marathon Key Colony Beach Boot Knights
Lower keys	Pigeon Money Little Duck Missouri Ohio Sunshine Bahia Honda Spanish Harbor Scout (West Summerland) No Name Big Pine Torch Little Middle Big Ramrod Summerland Knockemdown Cudjoe Sugarloaf Park Lower Sugarloaf Saddlebunch Shark Geiger Big Coppitt Island CDP East Rockland Rockland Boca Chica Raccoon Stock Island Island CDP Key West Sigsbee Fleming Sunset Wisteria
Outlying islands	Mule Keys Mule Crawfish Archer Joe Ingram Big Mullet Barracouta Cottrell Man Little Mullet Ballast Woman Boca Grande Marquesas Keys Dry Tortugas Loggerhead Key Tortugas Banks (submerged)
Areas	Florida Bay Dry Tortugas National Park Florida Keys National Marine Sanctuary National Key Deer Refuge John Pennekamp Coral Reef State Park Biscayne Bay Biscayne National Park Key West National Wildlife Refuge Great White Heron National Wildlife Refuge Crocodile Lake National Wildlife Refuge Florida Reef
Other topics	Monroe County Conch Republic Overseas Highway Overseas Railroad Card Sound Bridge Jewfish Creek Bridge Seven Mile Bridge Bahia Honda Rail Bridge Fort Jefferson Theater of the Sea 1935 Labor Day hurricane Hurricane Wilma Hurricane Irma Key Deer Key lime pie Florida Keys Keynoter Key West Citizen