Murari Gupta (fl. 16th century) was born in a Baidya family in Sylhet. He was a physician and noted Bengali Vaishnava poet. He became a devotee of Chaitanya Mahaprabhu and moved to Nabadwip.

In 1513, he composed in Sanskrit the Shri Krishna Chaitanya Charanamrita (Śrī-kṛṣṇa-caitanya-caraṇāmṛta a.k.a. murāri-gupta-kaṛchā), a poetic biography of Chaitanya Mahaprabhu. This work is the earliest source for Chaitanya's life. Later hagiographies are based on this work such as the Chaitanya Charitamrita.