|Preferred IUPAC name
3D model (JSmol)
CompTox Dashboard (EPA)
|Soluble to 100 mM in DMSO|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
what is ?)(
NBQX (2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) is an antagonist of the AMPA receptor.
NBQX blocks AMPA receptors in micromolar concentrations (~10–20 μM) and also blocks kainate receptors. In experiments, it is used to counter glutamate excitotoxicity. NBQX was found to have anticonvulsant activity in rodent seizure models.
As the disodium salt, NBQX is soluble in water at high concentrations (at least up to 100 mM).